A New Approach to 3-Substituted Indoles through Palladium-Catalyzed C-H Activation Followed by Intramolecular Amination Reaction of Enamines

被引：47

作者：

Inamoto, Kiyofumi ^{[1
]}

Saito, Tadataka ^{[1
]}

Hiroya, Kou ^{[1
]}

Doi, Takayuki ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan

来源：

SYNLETT | 2008年 / 20期

基金：

日本学术振兴会;

关键词：

palladium; catalysis; C-H activation; indoles; aminations;

D O I：

10.1055/s-0028-1087413

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamine compounds was achieved using a Pd(OAc)(2) (10 mol%)/Cu(OAc)(2) (100 mol%) catalyst system in DMSO. This work introduces an entirely new approach to 3-substituted indoles.

引用

页码：3157 / 3162

页数：6

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