Identification of Extended-Spectrum-β-Lactamase-Positive Klebsiella pneumoniae Urinary Tract Isolates Harboring KPC and CTX-M β-Lactamases in Nonhospitalized Patients

被引：10
|
作者：
Kopacz, Joanna [1 ]
Mariano, Noriel [1 ]
Colon-Urban, Rita [4 ]
Sychangco, Paul [1 ]
Wehbeh, Wehbeh [1 ,2 ]
Segal-Maurer, Sorana [1 ,2 ]
Urban, Carl [1 ,3 ]
机构：
[1] New York Hosp Queens, Dr James J Rahal Div Infect Dis, Flushing, NY USA
[2] Weill Cornell Med Coll, Dept Med, New York, NY USA
[3] New York Univ, Sch Med, Dept Microbiol, New York, NY USA
[4] SUNY Coll Old Westbury, Old Westbury, NY 11568 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2013年 / 57卷 / 10期
关键词：
ESCHERICHIA-COLI; MOLECULAR EPIDEMIOLOGY; HOSPITALIZED-PATIENTS; COMMUNITY; CARBAPENEMASE; INFECTIONS; RESIDENTS; AMERICA;
D O I：
10.1128/AAC.00043-13
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Forty-seven extended-spectrum-beta-lactamase-positive Klebsiella pneumoniae urinary tract isolates from nonhospitalized patients were identified, and 79% harbored KPC and/or CTX-M beta-lactamases. Approximately 90% of the isolates were resistant to trimethoprim-sulfamethoxazole and levofloxacin, and 40% were resistant to a carbapenem, while 92% were susceptible to polymyxin B, 87% were susceptible to tigecycline, and 79% were susceptible to fosfomycin. Increased use of broader-spectrum antibiotics may help to prevent their dissemination and reduce the risk of progression to invasive disease.
引用
收藏
页码：5166 / 5169
页数：4
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