Identification of Extended-Spectrum-β-Lactamase-Positive Klebsiella pneumoniae Urinary Tract Isolates Harboring KPC and CTX-M β-Lactamases in Nonhospitalized Patients

被引：10

作者：

Kopacz, Joanna ^{[1
]}

Mariano, Noriel ^{[1
]}

Colon-Urban, Rita ^{[4
]}

Sychangco, Paul ^{[1
]}

Wehbeh, Wehbeh ^{[1
,2
]}

Segal-Maurer, Sorana ^{[1
,2
]}

Urban, Carl ^{[1
,3
]}

机构：

[1] New York Hosp Queens, Dr James J Rahal Div Infect Dis, Flushing, NY USA

[2] Weill Cornell Med Coll, Dept Med, New York, NY USA

[3] New York Univ, Sch Med, Dept Microbiol, New York, NY USA

[4] SUNY Coll Old Westbury, Old Westbury, NY 11568 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2013年 / 57卷 / 10期

关键词：

ESCHERICHIA-COLI; MOLECULAR EPIDEMIOLOGY; HOSPITALIZED-PATIENTS; COMMUNITY; CARBAPENEMASE; INFECTIONS; RESIDENTS; AMERICA;

D O I：

10.1128/AAC.00043-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Forty-seven extended-spectrum-beta-lactamase-positive Klebsiella pneumoniae urinary tract isolates from nonhospitalized patients were identified, and 79% harbored KPC and/or CTX-M beta-lactamases. Approximately 90% of the isolates were resistant to trimethoprim-sulfamethoxazole and levofloxacin, and 40% were resistant to a carbapenem, while 92% were susceptible to polymyxin B, 87% were susceptible to tigecycline, and 79% were susceptible to fosfomycin. Increased use of broader-spectrum antibiotics may help to prevent their dissemination and reduce the risk of progression to invasive disease.

引用

页码：5166 / 5169

页数：4

共 37 条

[21] Detection of Extended Spectrum B-Lactamases in Urinary Isolates of Klebsiella pneumoniae in Relation to BlaSHV, BlaTEM and BlaCTX-M Gene Carriage
Eftekhar, F.
Rastegar, M.
Golalipoor, M.
MansourSamaei, N.
IRANIAN JOURNAL OF PUBLIC HEALTH, 2012, 41 (03) : 127 - 132
[22] Widespread Dissemination of Aminoglycoside Resistance Genes armA and rmtB in Klebsiella pneumoniae Isolates in Taiwan Producing CTX-M-Type Extended-Spectrum β-Lactamases
Ma, Ling
Lin, Chi-Jan
Chen, Jiun-Han
Fung, Chang-Phone
Chang, Feng-Yee
Lai, Yiu-Kay
Lin, Jung-Chung
Siu, L. K.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (01) : 104 - 111
[23] High Prevalence of CTX-M-15-Type Extended-Spectrum β-Lactamase Among AmpC β-Lactamase-Producing Klebsiella pneumoniae Isolates Causing Bacteremia in Korea
Cha, Min Kyeong
Kang, Cheol-In
Kim, So Hyun
Chung, Doo Ryeon
Peck, Kyong Ran
Lee, Nam Yong
Song, Jae-Hoon
MICROBIAL DRUG RESISTANCE, 2018, 24 (07) : 1002 - 1005
[24] Genetic environment of β-lactamase genes of extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates from patients with lower respiratory tract infection in China
Liu Lin
Wang Xiaorong
An Shuchang
Zhang Xiangyan
Chen Lin
Li Yuqian
Xu Li
Zhang Yijie
Gao Zhancheng
CHINESE MEDICAL JOURNAL, 2014, 127 (13) : 2445 - 2450
[25] High prevalence of 16S rRNA methylase RmtB among CTX-M extended-spectrum β-lactamase-producing Klebsiella pneumoniae from Islamabad, Pakistan
Habeeb, Muhammad Asif
Haque, Abdul
Nematzadeh, Shoeib
Iversen, Aina
Giske, Christian G.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2013, 41 (06) : 524 - 526
[26] Emergence and molecular characterization of multidrug-resistant Klebsiella pneumoniae isolates harboring blaCTX-M-15 extended-spectrum β-lactamases causing ventilator-associated pneumonia in China
Xu, Hui
Hu, Chunxiu
Sun, Yao
Zhou, Yiheng
Xiong, Yilin
Zhao, Zinan
Zhou, Qi
Sha, Li
Zhang, Beibei
Chen, Yang
INFECTION AND DRUG RESISTANCE, 2019, 12 : 33 - 43
[27] Prevalence of TEM, SHV, and CTX-M genes of extended-spectrum β-lactamase-producing Escherichia coli strains isolated from urinary tract infections in adults
Jena, Jayanti
Sahoo, Rajesh Kumar
Debata, Nagen Kumar
Subudhi, Enketeswara
3 BIOTECH, 2017, 7
[28] Multiresistant Uropathogenic Escherichia coli from a Region in India Where Urinary Tract Infections Are Endemic: Genotypic and Phenotypic Characteristics of Sequence Type 131 Isolates of the CTX-M-15 Extended-Spectrum-β-Lactamase-Producing Lineage
Hussain, Arif
Ewers, Christa
Nandanwar, Nishant
Guenther, Sebastian
Jadhav, Savita
Wieler, Lothar H.
Ahmed, Niyaz
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (12) : 6358 - 6365
[29] Urinary Tract Infections in Kidney Transplant Patients Due to Escherichia coli and Klebsiella pneumoniae-Producing Extended-Spectrum β-Lactamases: Risk Factors and Molecular Epidemiology
Espinar, Maria Jose
Miranda, Isabel M.
Costa-de-Oliveira, Sofia
Rocha, Rita
Rodrigues, Acacio G.
Pina-Vaz, Cidalia
PLOS ONE, 2015, 10 (08):
[30] Rapid Identification of Gram-Negative Bacteria with and without CTX-M Extended-Spectrum β-Lactamase from Positive Blood Culture Bottles by PCR Followed by Microchip Gel Electrophoresis
Fujita, Shin-ichi
Yosizaki, Kentaro
Ogushi, Thikako
Uechi, Kouhei
Takemori, Yukiko
Senda, Yasuko
JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (04) : 1483 - 1488

← 1 2 3 4 →