Erythroid/Megakaryocytic Differentiation Confers BCL-XL Dependency and Venetoclax Resistance in Acute Myeloid Leukemia

被引:0
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作者
Dufva, Olli [1 ,2 ]
Kuusanmaki, Heikki [3 ,4 ]
Vaha-Koskela, Markus [5 ]
Leppa, Aino-Maija [6 ]
Huuhtanen, Jani [7 ,8 ]
Vanttinen, Ida [3 ]
Nygren, Petra Johanna [1 ,2 ]
Klievink, Jay [1 ,2 ]
Bouhlal, Jonas [7 ]
Polonen, Petri [9 ]
Zhang, Qi [10 ]
Awad, Shady Adnan [7 ]
Mancebo, Cristina [11 ]
Saad, Joseph [6 ]
Miettinen, Juho J. [6 ]
Javarappa, Komal Kumar [6 ]
Aakko, Sofia [12 ]
Ruokoranta, Tanja [3 ]
Eldfors, Samuli [6 ]
Heinaniemi, Merja [13 ]
Wartiovaara-Kautto, Ulla [14 ,15 ]
Konopleva, Marina [10 ]
Keranen, Mikko A. [16 ]
Porkka, Kimmo [14 ,15 ]
Wennerberg, Krister [4 ,17 ]
Kontro, Mika [1 ,2 ,15 ,18 ]
Heckman, Caroline A. [6 ]
Mustjoki, Satu [1 ,2 ]
机构
[1] Univ Helsinki, Hematol Res Unit Helsinki, Helsinki, Finland
[2] Helsinki Univ Hosp, Comprehens Canc Ctr, Helsinki, Finland
[3] Univ Helsinki, HiLIFE, Lnstitute Mol Med Finland FIMM, Helsinki, Finland
[4] Univ Copenhagen, Biotech Res & Innovat Ctr BRIC, Copenhagen, Denmark
[5] Univ Helsinki, Helsinki Inst Life Sci, Insy Mol Med Finland, Helsinki, Finland
[6] Univ Helsinki, Helsinki Inst Life Sci, Inst Mol Med Finland FIMM, Helsinki, Finland
[7] Univ Helsinki, Dept Hematol, Hematol Res Unit Helsinki, Helsinki, Finland
[8] Aalto Univ, Dept Comp Sci, Sch Sci, Espoo, Finland
[9] St Jude Childrens Res Hosp, Dept Pathol, Memphis, TN USA
[10] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA
[11] Helsinki Inst Life Sci, Inst Mol Med Finland, Helsinki, Finland
[12] Inst Mol Med Finland FIMM, Helsinki, Finland
[13] Univ Eastern Finland, Sch Med, Inst Biomed, Kuopio, Finland
[14] Univ Helsinki, Dept Hematol, Hosp Comprehens Canc Ctr, Helsinki, Finland
[15] Univ Helsinki, Helsinki, Finland
[16] Univ Helsinki, Helsinki Univ Hosp, Dept Hematol, Comprehens Canc Ctr, Helsinki, Finland
[17] Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland
[18] Helsinki Univ Hosp, Comprehens Canc Ctr, Dept Hematol, Helsinki, Finland
关键词
D O I
10.1182/blood-2022-158694
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
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