Measurement of suprathreshold binocular interactions in amblyopia

被引:175
作者
Mansouri, B. [1 ]
Thompson, B. [1 ]
Hess, R. F. [1 ]
机构
[1] McGill Univ, Dept Ophthalmol, McGill Vis Res, Montreal, PQ H3A 1A1, Canada
关键词
Amblyopia; Global motion; Contrast; Binocular summation; Dichoptic interaction; Treatment of amblyopia; Global motion perception; Global form perception;
D O I
10.1016/j.visres.2008.09.002
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
It has been established that in amblyopia, information from the amblyopic eye (AME) is not combined with that from the fellow fixing eye (FFE) under conditions of binocular viewing. However, recent evidence suggests that mechanisms that combine information between the eyes are intact in amblyopia. The lack of binocular function is most likely due to the imbalanced inputs from the two eyes under binocular conditions [Baker, D. H., Meese, T. S., Mansouri, B., & Hess, R. F. (2007b). Binocular summation of contrast remains intact in strabismic amblyopia. Investigative Ophthalmology & Visual Science, 48(11), 5332-5338]. We have measured the extent to which the information presented to each eye needs to differ for binocular combination to occur and in doing so we quantify the influence of interocular suppression. We quantify these suppressive effects for suprathreshold processing of global stimuli for both motion and spatial tasks. The results confirm the general importance of these suppressive effects in rendering the structurally binocular visual system of a strabismic amblyope, functionally monocular. (C) 2008 Published by Elsevier Ltd.
引用
收藏
页码:2775 / 2784
页数:10
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