Organization of the Hox gene cluster in the grasshopper, Schistocerca gregaria

被引：46

作者：

Ferrier, DEK ^{[1
]}

Akam, M ^{[1
]}

机构：

[1] DEPT GENET,CAMBRIDGE CB2 1QR,ENGLAND

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1996年 / 93卷 / 23期

基金：

英国惠康基金;

关键词：

fluorescent in situ hybridization; pulsed-field gel electrophoresis; accessory genes; gene linkage;

D O I：

10.1073/pnas.93.23.13024

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The conserved organization of the Hox genes throughout the animal kingdom has become one of the major paradigms of evolutionary developmental biology. We have examined the organization of the Hox genes of the grasshopper, Schistocerca gregaria. We find that the grasshopper Hox cluster is over 700 kb long, and is not split into equivalents of the Antennapedia complex and the bithorax complex of Drosophila melanogaster. SgDax and probably also Sgzen, the grasshopper homologues of fushi-tarazu (ftz) and Zerknullt (zen), respectively, are also in the cluster, showing that the non-homeotic Antp-class genes, ''accessory genes,'' are an ancient feature of insect Hox clusters.

引用

页码：13024 / 13029

页数：6

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