Functional genomics

被引：61

作者：

Fields, S

Kohara, Y

Lockhart, DJ

机构：

[1] Univ Washington, Howard Hughes Med Inst, Dept Genet, Seattle, WA 98195 USA

[2] Univ Washington, Howard Hughes Med Inst, Dept Med, Seattle, WA 98195 USA

[3] Natl Inst Genet, Genome Biol Lab, Mishima, Shizuoka 411, Japan

[4] Affymetrix Inc, Santa Clara, CA 95051 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1999年 / 96卷 / 16期

关键词：

D O I：

10.1073/pnas.96.16.8825

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Complete genome sequences are providing a framework to allow the investigation of biological processes by the use of comprehensive approaches. Genome analysis also is having a dramatic impact on medicine through its identification of genes and mutations involved in disease and the elucidation of entire microbial gene sets. Studies of the sequences of model organisms, such as that of the nematode worm Caenorhabditis elegans, are providing extraordinary insights into development and differentiation that aid the study of these processes in humans. The field of functional genomics seeks to devise and apply technologies that take advantage of the growing body of sequence information to analyze the full complement of genes and proteins encoded by an organism.

引用

收藏

页码：8825 / 8826

页数：2

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