A DAST-free route to aryl(difluoromethyl)phosphonic esters

被引：15
作者：
Blades, K
Cockerill, GS
Easterfield, HJ
Lequeux, TP
Percy, JM
机构：
[1] UNIV BIRMINGHAM,SCH CHEM,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND
[2] GLAXO WELLCOME RES & DEV LTD,STEVENAGE SG1 2NY,HERTS,ENGLAND
来源：
CHEMICAL COMMUNICATIONS | 1996年 / 14期
关键词：
D O I：
10.1039/cc9960001615
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The cerium(III)-mediated addition of diethyl (lithiodifluoromethyl)phosphonate to a benzoquinone monoketal allows the synthesis of phenol bearing the (diethoxyphosphonyl)difluoromethyl group via short, scaleable reaction sequences which avoid the use of the DAST reagent.
引用
收藏
页码：1615 / 1616
页数：2
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