Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells

被引：13
作者：
Mitsui, Taichi [1 ]
Hotta, Sho [1 ]
Tazawa, Shigemi [1 ]
Arai, Yasuko [1 ]
Kato, Kenji [1 ]
Ichihara, Kenji [1 ]
机构：
[1] Api Co Ltd, Nagaragawa Res Ctr, Gifu, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2018年 / 82卷 / 03期
关键词：
Brazilian propolis; Bahia state; 2-Phenoxychromone; anti-cancer; CINNAMIC ACID-DERIVATIVES; ARTEPILLIN-C; IDENTIFICATION; EXTRACT; ANTIBACTERIAL; ARREST;
D O I：
10.1080/09168451.2018.1427550
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A novel 2-phenoxychromone (1) and five known flavones (2-6) were isolated from northeastern Brazilian propolis in the state of Bahia. The chemical structures of these six compounds were determined by spectroscopic investigations and single-crystal X-ray analysis. The isolated compounds showed growth-inhibitory activities, in varying degrees, against human tumor cell lines. This is the first report on the discovery of a novel 2-phenoxychromone from propolis.
引用
收藏
页码：417 / 421
页数：5
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