Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells

被引：13

作者：

Mitsui, Taichi ^{[1
]}

Hotta, Sho ^{[1
]}

Tazawa, Shigemi ^{[1
]}

Arai, Yasuko ^{[1
]}

Kato, Kenji ^{[1
]}

Ichihara, Kenji ^{[1
]}

机构：

[1] Api Co Ltd, Nagaragawa Res Ctr, Gifu, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2018年 / 82卷 / 03期

关键词：

Brazilian propolis; Bahia state; 2-Phenoxychromone; anti-cancer; CINNAMIC ACID-DERIVATIVES; ARTEPILLIN-C; IDENTIFICATION; EXTRACT; ANTIBACTERIAL; ARREST;

D O I：

10.1080/09168451.2018.1427550

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel 2-phenoxychromone (1) and five known flavones (2-6) were isolated from northeastern Brazilian propolis in the state of Bahia. The chemical structures of these six compounds were determined by spectroscopic investigations and single-crystal X-ray analysis. The isolated compounds showed growth-inhibitory activities, in varying degrees, against human tumor cell lines. This is the first report on the discovery of a novel 2-phenoxychromone from propolis.

引用

页码：417 / 421

页数：5

共 32 条

[1] ISOLATION AND IDENTIFICATION OF ANTIMICROBIAL COMPOUNDS IN BRAZILIAN PROPOLIS [J].