Hollow Fiber System Model for Tuberculosis: The European Medicines Agency Experience

被引：31
作者：
Cavaleri, Marco [1 ]
Manolis, Efthymios [2 ]
机构：
[1] European Med Agcy, Human Med Evaluat Div, Antiinfect & Vaccines, London, England
[2] European Med Agcy, Human Med Res & Dev Support Div Sci Advice, London, England
来源：
CLINICAL INFECTIOUS DISEASES | 2015年 / 61卷
关键词：
tuberculosis; PK/PD; in vitro models; EMA; qualification;
D O I：
10.1093/cid/civ484
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The in vitro hollow fiber system model has been qualified by the European Medicines Agency as a methodology for use in support of selection and development of antituberculosis regimens. More data are expected to be generated in the future to further characterize its value.
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收藏
页码：S1 / S4
页数：4
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