Hollow Fiber System Model for Tuberculosis: The European Medicines Agency Experience

被引：33

作者：

Cavaleri, Marco ^{[1
]}

Manolis, Efthymios ^{[2
]}

机构：

[1] European Med Agcy, Human Med Evaluat Div, Antiinfect & Vaccines, London, England

[2] European Med Agcy, Human Med Res & Dev Support Div Sci Advice, London, England

来源：

CLINICAL INFECTIOUS DISEASES | 2015年 / 61卷

关键词：

tuberculosis; PK/PD; in vitro models; EMA; qualification;

D O I：

10.1093/cid/civ484

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The in vitro hollow fiber system model has been qualified by the European Medicines Agency as a methodology for use in support of selection and development of antituberculosis regimens. More data are expected to be generated in the future to further characterize its value.

引用

页码：S1 / S4

页数：4

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