Solid supported palladium(0) nano/microparticle: a ligand-free efficient recyclable heterogeneous catalyst for mono- and β,β-double-Heck reaction

被引：21
作者：
Sharma, Dharminder [1 ]
Kumar, Sandeep [1 ]
Shil, Arun K. [1 ]
Guha, Nitul Ranjan [1 ]
Bandna [1 ]
Das, Pralay [1 ]
机构：
[1] CSIR Inst Himalayan Bioresource Technol, Nat Plant Prod Div, Palampur 176061, Himachal Prades, India
来源：
TETRAHEDRON LETTERS | 2012年 / 53卷 / 52期
关键词：
Heck; Heterogeneous catalyst; Solid supported palladium (SS-Pd); Nano/microparticles; Mono- and beta; beta-double-Heck; HECK REACTION; STEREOSELECTIVE-SYNTHESIS; DOUBLE ARYLATIONS; THIAZOLO; PLATFORM; OLEFINS; CARBON;
D O I：
10.1016/j.tetlet.2012.10.062
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Solid supported palladium nano/microparticles were found to be active catalysts to perform mono- and beta,beta-double-Heck reactions. Different beta-unsubstituted and substituted alkenes including acrylate, methacrylate, crotonate, styrene, acrylonitrile, and acrylamide were investigated successfully for mono- and beta,beta-double-Heck reactions with aryl iodide under milder reaction condition. One-pot beta,beta-double-Heck reaction of aryl iodides with alpha,beta-unsaturated ester, amide, nitrile, and styrene derivatives were also performed under standard reaction conditions. Wide functional group tolerance, easy catalyst recovery, and recyclability up to twelve times without significant loss of catalytic activity added extra importance to the present process. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7044 / 7051
页数：8
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