Potential Analysis of Smart Flow Processing and Micro Process Technology for Fastening Process Development: Use of Chemistry and Process Design as Intensification Fields

被引:93
|
作者
Hessel, Volker [1 ]
Gursel, Iris Vural [1 ]
Wang, Qi [1 ]
Noel, Timothy [1 ]
Lang, Juergen [2 ]
机构
[1] Eindhoven Univ Technol, Dept Chem Engn & Chem Micro Flow Chem & Proc Tech, NL-5600 MB Eindhoven, Netherlands
[2] Evon Ind AG, Innovat Management Verfahrenstech & Engn, Hanau, Germany
基金
欧洲研究理事会;
关键词
Adipic acid; Flow miniplants; Future Factory; Micro process technology; Process intensification; INCLUDING MS DESIGN; HIGH-PRESSURE; CAPILLARY ELECTROCHROMATOGRAPHY; PROCESS WINDOWS; ADIPIC ACID; MICROREACTOR TECHNOLOGY; ORGANIC-SYNTHESIS; DIRECT OXIDATION; GENERAL-METHOD; COST-ANALYSIS;
D O I
10.1002/ceat.201200038
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
Flow processes with microstructured reactors allow paradigm changes in process development and thus can enable a faster development time to the final production plant. They do this by exploiting similarity effects along the development chain (modularity) and intensification. The final result can be a (significantly) reduced number of apparatus in the plant, a (significantly) reduced apparatus size, and a higher predictability in the scale-out of the apparatus. So far, this was mainly achieved via transport intensification given in microstructured reactors improved mixing and heat transfer which increase productivity and possibly improve selectivity. A more new idea is chemical intensification through deliberate use of harsh chemistries at unusual (high) pressure, temperature, concentration, and reaction environment which again increases productivity. A very new idea is the process design intensification the reaction-maximized flow processes need less separation expenditure and the small unit size together with the high degree in functionality gives large potential for system integration. Both means change and simplify the process scheme totally which can lead to a reduced number of apparatus and has impact on predictability. The modular nature of the small flow units allow an easy implementation to modern modular plant environments (Future Factories) which enables to perform all the testing cycles (lab, pilot, production) in one plant environment; an example are here container plants. All these measures have large potential for (much) decreased overall development time.
引用
收藏
页码:1184 / 1204
页数:21
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