Circadian rhythms in obsessive-compulsive disorder

被引：21

作者：

Lange, Klaus W. ^{[1
,2
]}

Lange, Katharina M. ^{[1
]}

Hauser, Joachim ^{[1
]}

Tucha, Lara ^{[2
]}

Tucha, Oliver ^{[2
]}

机构：

[1] Univ Regensburg, Dept Expt Psychol, D-93040 Regensburg, Germany

[2] Univ Groningen, Dept Dev & Clin Neuropsychol, Groningen, Netherlands

来源：

JOURNAL OF NEURAL TRANSMISSION | 2012年 / 119卷 / 10期

关键词：

Obsessive-compulsive disorder (OCD); Circadian rhythm; Hormone dysregulation; Delayed sleep phase; Agomelatine; Chronotherapy; DEXAMETHASONE-SUPPRESSION TEST; CORTICOTROPIN-RELEASING-FACTOR; DELAYED SLEEP PHASE; CEREBROSPINAL-FLUID; TOURETTES-SYNDROME; SUCCESSFUL AUGMENTATION; NEUROACTIVE STEROIDS; CORTISOL; NEUROSTEROIDS; MELATONIN;

D O I：

10.1007/s00702-012-0805-z

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The etiopathology and neurobiology of obsessive-compulsive disorder (OCD) are not fully understood. As for altered circadian rhythms associated with OCD, hormonal dysregulation and a delayed sleep phase have come into the focus of research. The novel antidepressant agomelatine is able to resynchronize circadian rhythms and the augmentative administration of this compound has been shown to be of benefit in some OCD patients who are refractory to common forms of pharmacotherapy. Adjunctive chronotherapy might also enhance the outcome in treatment-refractory OCD. The present review summarises the findings regarding circadian abnormalities in OCD.

引用

页码：1077 / 1083

页数：7

共 83 条

[1]

ALTEMUS M, 1992, ARCH GEN PSYCHIAT, V49, P9

[2] CORTICOTROPIN-RELEASING FACTOR STIMULATION TEST IN OBSESSIVE-COMPULSIVE DISORDER [J].

BAILLY, D ;

SERVANT, D ;

DEWAILLY, D ;

BEUSCART, R ;

RACADOT, A ;

FOSSATI, P ;

PARQUET, PJ .

BIOLOGICAL PSYCHIATRY, 1994, 35 (02) :143-146

[3] Effect of dehydroepiandrosterone on central and peripheral levels of allopregnanolone and ß-endorphin [J].

Bernardi, F ;

Casarosa, E ;

Pluchino, N ;

Palumbo, I ;

Genazzani, AD ;

Luisi, SF ;

Genazzani, AR .

FERTILITY AND STERILITY, 2005, 83 :1161-1168

[4] Dysregulation of neurosteroids in obsessive compulsive disorder [J].

Bigos, K. L. ;

Folan, M. M. ;

Jones, M. R. ;

Haas, G. L. ;

Kroboth, F. J. ;

Kroboth, P. D. .

JOURNAL OF PSYCHIATRIC RESEARCH, 2009, 43 (04) :442-445

[5] A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder [J].

Bloch, M. H. ;

Landeros-Weisenberger, A. ;

Kelmendi, B. ;

Coric, V. ;

Bracken, M. B. ;

Leckman, J. F. .

MOLECULAR PSYCHIATRY, 2006, 11 (07) :622-632

[6] Reported sleep patterns in obsessive compulsive disorder (OCD) [J].

Bobdey, M ;

Fineberg, N ;

Gale, TM ;

Patel, A ;

Davies, HA .

INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE, 2002, 6 (01) :15-21

[7] VIP NEURONS AS PRIME SYNAPTIC TARGETS FOR SEROTONIN AFFERENTS IN RAT SUPRACHIASMATIC NUCLEUS - A COMBINED AUTORADIOGRAPHIC AND IMMUNOCYTOCHEMICAL STUDY [J].

BOSLER, O ;

BEAUDET, A .

JOURNAL OF NEUROCYTOLOGY, 1985, 14 (05) :749-763

[8] DEXAMETHASONE SUPPRESSION TEST IN PATIENTS WITH PRIMARY OBSESSIVE-COMPULSIVE DISORDER AND IN HEALTHY CONTROLS [J].

CATAPANO, F ;

MONTELEONE, P ;

MAJ, M ;

KEMALI, D .

NEUROPSYCHOBIOLOGY, 1990, 23 (02) :53-56

[9] MELATONIN AND CORTISOL SECRETION IN PATIENTS WITH PRIMARY OBSESSIVE-COMPULSIVE DISORDER [J].

CATAPANO, F ;

MONTELEONE, P ;

FUSCHINO, A ;

MAJ, M ;

KEMALI, D .

PSYCHIATRY RESEARCH, 1992, 44 (03) :217-225

[10] Clinical outcome in patients with bipolar I disorder, obsessive compulsive disorder or both [J].

Centorrino, F ;

Hennen, J ;

Mallya, G ;

Egli, S ;

Clark, T ;

Baldessarini, RJ .

HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, 2006, 21 (03) :189-193

← 1 2 3 4 5 6 7 8 9 →