Animal models in endometriosis experimental research

被引：6

作者：

Colette, S. ^{[1
]}

Donnez, J. ^{[1
]}

机构：

[1] Catholic Univ Louvain, Inst Rech Expt & Clin, Dept Gynecol, Pole Rech Gynecol,Clin Univ St Luc, B-1200 Brussels, Belgium

来源：

GYNECOLOGIE OBSTETRIQUE & FERTILITE | 2012年 / 40卷 / 09期

关键词：

Endometriosis; Animal model; MURINE MODEL; BABOON MODEL; PAPIO-ANUBIS; MOUSE MODEL; LESIONS; GROWTH; CYNOCEPHALUS; INHIBITION; MICE;

D O I：

10.1016/j.gyobfe.2012.07.009

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Sampson's menstrual reflux theory is commonly used to explain the origin of endometriotic lesions in women. However, their pathogenesis remains largely unknown. Validated research models need to be developed with the aim of studying mechanisms by which endometrial cells from menstrual reflux implant and grow, and investigating if potential new markers or molecules could be envisaged as diagnostic or therapeutic tools. The present review looks at the different existing murine and non-human primate models of endometriosis, and evaluates their principal uses. (C) 2012 Elsevier Masson SAS. All rights reserved.

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收藏

页码：494 / 496

页数：3

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