Iron-catalysed Negishi coupling of benzyl halides and phosphates

被引：154

作者：

Bedford, Robin B. ^{[1
]}

Huwe, Michael ^{[1
]}

Wilkinson, Mark C. ^{[2
]}

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

[2] GlaxoSmithKline Inc, Chem Dev, Stevenage SG1 2NY, Herts, England

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 05期

基金：

英国工程与自然科学研究理事会;

关键词：

ARYL GRIGNARD-REAGENTS; SECONDARY ALKYL-HALIDES; BEARING BETA-HYDROGENS; DIHYDROFOLATE-REDUCTASE; ARYLBORONIC ACIDS; PNEUMOCYSTIS-CARINII; ARYLMAGNESIUM REAGENTS; MYCOBACTERIUM-AVIUM; TOXOPLASMA-GONDII; INHIBITORS;

D O I：

10.1039/b818961g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iron-based catalysts containing either 1,2-bis(diphenylphosphino)benzene or 1,3-bis(diphenylphosphino)propane give excellent activity and good selectivity in the Negishi coupling of aryl zinc reagents with a range of benzyl halides and phosphates.

引用

页码：600 / 602

页数：3

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