MLN4924, a potent and novel small molecule inhibitor of Nedd8 activating enzyme, induces DNA re-replication and apoptosis in cultured human tumor cells

被引:0
|
作者
Milhollen, M. [1 ]
Narayanan, U. [1 ]
Amidon, B. [1 ]
Berger, A. [2 ]
Langston, S. [3 ]
Soucy, T. [4 ]
Smith, P. [4 ]
机构
[1] Millennium Pharmaceut Inc, Mol & Cellular Oncol, Cambridge, MA USA
[2] Millennium Pharmaceut Inc, Canc Pharmacol, Cambridge, MA USA
[3] Millennium Pharmaceut Inc, Chem, Cambridge, MA USA
[4] Millennium Pharmaceut Inc, Biochem, Cambridge, MA USA
来源
EJC SUPPLEMENTS | 2008年 / 6卷 / 12期
关键词
D O I
10.1016/S1359-6349(08)72290-0
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:113 / 113
页数:1
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