Positron Emission Tomography-Based Response to Target and Immunotherapies in Oncology

被引：11
作者：
Donegani, Maria Isabella [1 ,2 ]
Ferrarazzo, Giulia [1 ,2 ]
Marra, Stefano [1 ,2 ]
Miceli, Alberto [1 ,2 ]
Raffa, Stefano [1 ,2 ]
Bauckneht, Matteo [1 ,2 ]
Morbelli, Silvia [1 ,2 ]
机构：
[1] Univ Genoa, Nucl Med Unit, Dept Hlth Sci, I-16132 Genoa, Italy
[2] IRCCS Osped Policlin San Martino, I-16132 Genoa, Italy
来源：
MEDICINA-LITHUANIA | 2020年 / 56卷 / 08期
关键词：
positron emission tomography; target therapy; immunotherapy; response assessment; PERCIST criteria; RESISTANT PROSTATE-CANCER; METABOLIC TUMOR VOLUME; CELL LUNG-CANCER; F-18-FDG PET/CT; FDG-PET; EARLY PREDICTION; EVALUATION CRITERIA; HODGKINS LYMPHOMA; IN-VIVO; MELANOMA;
D O I：
10.3390/medicina56080373
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2-deoxy-2-[F-18]fluoro-D-glucose ([F-18]FDG) is a promising tool to support the evaluation of response to either target therapies or immunotherapy with immune checkpoint inhibitors both in clinical trials and, in selected patients, at the single patient's level. The present review aims to discuss available evidence related to the use of [F-18]FDG PET (Positron Emission Tomography) to evaluate the response to target therapies and immune checkpoint inhibitors. Criteria proposed for the standardization of the definition of the PET-based response and complementary value with respect to morphological imaging are commented on. The use of PET-based assessment of the response through metabolic pathways other than glucose metabolism is also relevant in the framework of personalized cancer treatment. A brief discussion of the preliminary evidence for the use of non-FDG PET tracers in the evaluation of the response to new therapies is also provided.
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页码：1 / 22
页数：23
相关论文
共 96 条
  • [41] 18F-FDG PET/CT for Monitoring of Ipilimumab Therapy in Patients with Metastatic Melanoma
    Ito, Kimiteru
    Teng, Rebecca
    Schoder, Heiko
    Humm, John L.
    Ni, Ai
    Michaud, Laure
    Nakajima, Reiko
    Yamashita, Rikiya
    Wolchok, Jedd D.
    Weber, Wolfgang A.
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2019, 60 (03) : 335 - 341
  • [42] Personalised cancer medicine
    Jackson, Sarah E.
    Chester, John D.
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2015, 137 (02) : 262 - 266
  • [43] 18F-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer
    Jreige, Mario
    Letovanec, Igor
    Chaba, Kariman
    Renaud, Stephanie
    Rusakiewicz, Sylvie
    Cristina, Valerie
    Peters, Solange
    Krueger, Thorsten
    de Leval, Laurence
    Kandalaft, Lana E.
    Nicod-Lalonde, Marie
    Romero, Pedro
    Prior, John O.
    Coukos, George
    Schaefer, Niklaus
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2019, 46 (09) : 1859 - 1868
  • [44] Metabolic activity by 18F-FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC
    Kaira, Kyoichi
    Higuchi, Tetsuya
    Naruse, Ichiro
    Arisaka, Yukiko
    Tokue, Azusa
    Altan, Bolag
    Suda, Satoshi
    Mogi, Akira
    Shimizu, Kimihiro
    Sunaga, Noriaki
    Hisada, Takeshi
    Kitano, Shigehisa
    Obinata, Hideru
    Yokobori, Takehiko
    Mori, Keita
    Nishiyama, Masahiko
    Tsushima, Yoshihito
    Asao, Takayuki
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2018, 45 (01) : 56 - 66
  • [45] Why Are Cancer Drugs So Expensive in the United States, and What Are the Solutions?
    Kantarjian, Hagop
    Rajkumar, S. Vincent
    [J]. MAYO CLINIC PROCEEDINGS, 2015, 90 (04) : 500 - 504
  • [46] The quest for improving the management of breast cancer by functional imaging: The discovery and development of 16α-[18F]fluoroestradiol (FES), a PET radiotracer for the estrogen receptor, a historical review
    Katzenellenbogen, John A.
    [J]. NUCLEAR MEDICINE AND BIOLOGY, 2021, 92 : 24 - 37
  • [47] Kitajima K, 2019, ACTA MED OKAYAMA, V73, P341, DOI 10.18926/AMO/56936
  • [48] Residual FDG-PET metabolic activity in metastatic melanoma patients with prolonged response to anti-PD-1 therapy
    Kong, Benjamin Y.
    Menzies, Alexander M.
    Saunders, Catherine A. B.
    Liniker, Elizabeth
    Ramanujam, Sangeetha
    Guminski, Alex
    Kefford, Richard F.
    Long, Georgina V.
    Carlino, Matteo S.
    [J]. PIGMENT CELL & MELANOMA RESEARCH, 2016, 29 (05) : 572 - 577
  • [49] Kruse V, 2015, Q J NUCL MED MOL IM, V59, P462
  • [50] Between-Patient and Within-Patient (Site-to-Site) Variability in Estrogen Receptor Binding, Measured In Vivo by 18F-Fluoroestradiol PET
    Kurland, Brenda F.
    Peterson, Lanell M.
    Lee, Jean H.
    Linden, Hannah M.
    Schubert, Erin K.
    Dunnwald, Lisa K.
    Link, Jeanne M.
    Krohn, Kenneth A.
    Mankoff, David A.
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2011, 52 (10) : 1541 - 1549
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