New genetic markers for male fertility

被引：25

作者：

Ferlin, Alberto ^{[1
,2
]}

机构：

[1] Univ Padua, Dept Mol Med, I-35121 Padua, Italy

[2] Univ Padua, Ctr Human Reprod Pathol, I-35121 Padua, Italy

来源：

ASIAN JOURNAL OF ANDROLOGY | 2012年 / 14卷 / 06期

关键词：

MALE-INFERTILITY; HUMANS;

D O I：

10.1038/aja.2012.84

中图分类号：

R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

摘要：

Studies in the last years definitively demonstrate the high prevalence of genetic causes of spermatogenic impairment. A large proportion of infertile males does not receive a clear diagnosis and are reported as idiopathic or unexplained, also because standard semen analysis cannot clearly distinguish fertile from infertile populations. Researches aimed at identifying new potential genetic markers of sperm fertilizing ability and male fertility are therefore necessary. Two recent papers addressed these questions and provided interesting results on new possible genetic factors involved in male fertility and as prognostic markers of fertilizing potential of human spermatozoa.

引用

页码：807 / 808

页数：2

共 7 条

[1] Sperm gene expression profile is related to pregnancy rate after insemination and is predictive of low fecundity in normozoospermic men [J].