Do day-3 embryo grade predict day-5 blastocyst transfer outcomes in patients with good prognosis?

被引:13
作者
Li, Mingzhao [1 ]
Wang, Yingjin [2 ]
Shi, Juanzi [1 ]
机构
[1] Northwest Womens & Childrens Hosp, ART Ctr, Xian, Shaanxi, Peoples R China
[2] Northwest Womens & Childrens Hosp, Med Ultrasound Ctr, Xian, Shaanxi, Peoples R China
关键词
Conventional morphology; elective single blastocyst transfer; good prognosis; time-lapse monitoring; TIME-LAPSE MICROSCOPY; PREGNANCY; MORPHOLOGY; IVF;
D O I
10.1080/09513590.2018.1484444
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The main aim was to investigate whether or not day-3 embryo grade could predict day-5 blastocyst transfer outcomes in patients with good prognosis. This study included 233 elective single blastocyst transfers (eSBT) by D5 selection with conventional morphology (CM) and 121 elective single blastocyst transfers (eSBT) by D5 selection with time-lapse monitoring system (TL) from October 2016 to October 2017. All the patients were submitted to controlled ovarian stimulation (COS) with long-term protocol and transferred for the first time. The main outcome measures were clinical pregnancy rates (CPR) and ongoing pregnancy (OPR). Our results suggested that CPR (58.04 versus 57.89 versus 55.56%; p = .957) and OPR (66.07 versus 65.79 versus 64.44%; p = .981) were comparable among day 3 grades I, grades II, and grades III groups. We also observed that the TL group showed a slightly better CPR and OPR than CM group (p > .05). Our findings suggested that good or poor embryos at day-3 were not predictive of the outcomes of good-quality blastocysts in a good-prognosis population. It needed to be emphasized that time-lapse monitoring might be useful for elective single blastocyst transfer.
引用
收藏
页码:36 / 39
页数:4
相关论文
共 18 条
  • [1] The importance of the cleavage stage morphology evaluation for blastocyst transfer in patients with good prognosis
    Braga, Daniela P. A. F.
    Setti, Amanda S.
    Figueira, Rita C. S.
    Iaconelli, Assumpto, Jr.
    Borges, Edson, Jr.
    [J]. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2014, 31 (08) : 1105 - 1110
  • [2] Gardner DK, 1998, HUM REPROD, V13, P3289
  • [3] Göçmen A, 2015, INT J CLIN EXP MED, V8, P6272
  • [4] Should we consider day-2 and day-3 embryo morphology before day-5 transfer when blastocysts reach a similar good quality?
    Herbemont, Charlene
    Sarandi, Solmaz
    Boujenah, Jeremy
    Cedrin-Durnerin, Isabelle
    Sermondade, Nathalie
    Vivot, Alexandre
    Poncelet, Christophe
    Grynberg, Michael
    Sifer, Christophe
    [J]. REPRODUCTIVE BIOMEDICINE ONLINE, 2017, 35 (05) : 521 - 528
  • [5] Time lapse microscopy is useful for elective single-embryo transfer
    Herzberger, Einat Haikin
    Ghetler, Yehudith
    Yaniv, Rina Tamir
    Berkovitz, Arie
    Gonen, Ofer
    Cohen, Ilan
    Shulman, Adrian
    Wiser, Amir
    [J]. GYNECOLOGICAL ENDOCRINOLOGY, 2016, 32 (10) : 816 - 818
  • [6] A pilot randomized controlled trial of Day 3 single embryo transfer with adjunctive time-lapse selection versus Day 5 single embryo transfer with or without adjunctive time-lapse selection
    Kaser, Daniel J.
    Bormann, Charles L.
    Missmer, Stacey A.
    Farland, Leslie V.
    Ginsburg, Elizabeth S.
    Racowsky, Catherine
    [J]. HUMAN REPRODUCTION, 2017, 32 (08) : 1598 - 1603
  • [7] Kim HJ, 2017, CLIN EXP REPROD MED, V44, P90, DOI 10.5653/cerm.2017.44.2.90
  • [8] Pregnancy-related mortality among women with multifetal pregnancies
    MacKay, Andrea R.
    Berg, Cynthia J.
    King, Jeffrey C.
    Duran, Catherine
    Chang, Jeani
    [J]. OBSTETRICS AND GYNECOLOGY, 2006, 107 (03) : 563 - 568
  • [9] The use of morphokinetics as a predictor of embryo implantation
    Meseguer, Marcos
    Herrero, Javier
    Tejera, Alberto
    Hilligsoe, Karen Marie
    Ramsing, Niels Birger
    Remohi, Jose
    [J]. HUMAN REPRODUCTION, 2011, 26 (10) : 2658 - 2671
  • [10] THE RISKS CONFRONTING TWINS - A NATIONAL PERSPECTIVE
    POWERS, WF
    KIELY, JL
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1994, 170 (02) : 456 - 461