Pyrrolothieno[1,4]diazepines .3. Synthesis of amino, hydrazino and mercapto derivatives

被引：7

作者：

Boulouard, M

Rault, S

Dallemagne, P

Alsaidi, A

Robba, M

机构：

[1] Ctr. d'Etud. Rech. Medicament N., U.F.R. des Sciences Pharmaceutiques, 14032 Caen

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1996年 / 33卷 / 01期

关键词：

D O I：

10.1002/jhet.5570330115

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of 2-(2-formyl-1H-pyrrol-1-yl)-3-thiophenecarbonitrile by sodium percarbonate afforded, in a one-pot sequence and on a multigram scale, 5,6-dihydro-6-hydroxy-4H-pyrrolo[1,2-a]thieno-[3,2-f][1,4]diazepin-4-one whose reactivity towards various nucleophiles like amines, hydrazines and thiols was evaluated.

引用

页码：87 / 91

页数：5