Matrix metalloproteinases - Are they antiatherogenic but proaneurysmal?

被引:20
作者
Bendeck, MP [1 ]
机构
[1] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON M5S 1A8, Canada
关键词
matrix metalloproteinases; vascular remodeling; aneurysm; atherosclerosis;
D O I
10.1161/01.RES.0000018141.73992.41
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:836 / 837
页数:2
相关论文
共 24 条
  • [1] Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model
    Allaire, E
    Forough, R
    Clowes, W
    Starcher, B
    Clowes, AW
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (07) : 1413 - 1420
  • [2] Inhibition of matrix metalloproteinase activity inhibits smooth muscle cell migration but not neointimal thickening after arterial injury
    Bendeck, MP
    Irvin, C
    Reidy, MA
    [J]. CIRCULATION RESEARCH, 1996, 78 (01) : 38 - 43
  • [3] Doxycycline modulates smooth muscle cell growth, migration, and matrix remodeling after arterial injury
    Bendeck, MP
    Conte, M
    Zhang, MY
    Nili, N
    Strauss, BH
    Farwell, SM
    [J]. AMERICAN JOURNAL OF PATHOLOGY, 2002, 160 (03) : 1089 - 1095
  • [4] Overexpression of tissue inhibitor of matrix metalloproteinase-1 inhibits vascular smooth muscle cell functions in vitro and in vivo
    Forough, R
    Koyama, N
    Hasenstab, D
    Lea, H
    Clowes, M
    Nikkari, ST
    Clowes, AW
    [J]. CIRCULATION RESEARCH, 1996, 79 (04) : 812 - 820
  • [5] INCREASED EXPRESSION OF MATRIX METALLOPROTEINASES AND MATRIX-DEGRADING ACTIVITY IN VULNERABLE REGIONS OF HUMAN ATHEROSCLEROTIC PLAQUES
    GALIS, ZS
    SUKHOVA, GK
    LARK, MW
    LIBBY, P
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1994, 94 (06) : 2493 - 2503
  • [6] Matrix metalloproteinases in vascular remodeling and atherogenesis - The good, the bad, and the ugly
    Galis, ZS
    Khatri, JJ
    [J]. CIRCULATION RESEARCH, 2002, 90 (03) : 251 - 262
  • [7] MACROPHAGE FOAM CELLS FROM EXPERIMENTAL ATHEROMA CONSTITUTIVELY PRODUCE MATRIX-DEGRADING PROTEINASES
    GALIS, ZS
    SUKHOVA, GK
    KRANZHOFER, R
    CLARK, S
    LIBBY, P
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (02) : 402 - 406
  • [8] Gene transfer of tissue inhibitor of metalloproteinase-2 inhibits metalloproteinase activity and neointima formation in human saphenous veins
    George, SJ
    Baker, AH
    Angelini, GD
    Newby, AC
    [J]. GENE THERAPY, 1998, 5 (11) : 1552 - 1560
  • [9] Type VIII collagen stimulates smooth muscle cell migration and matrix metalloproteinase synthesis after arterial injury
    Hou, GP
    Mulholland, D
    Gronska, MA
    Bendeck, MP
    [J]. AMERICAN JOURNAL OF PATHOLOGY, 2000, 156 (02) : 467 - 476
  • [10] ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis
    Lemaître, V
    O'Byrne, TK
    Borczuk, AC
    Okada, Y
    Tall, AR
    D'Armiento, J
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (10) : 1227 - 1234