Engineering Approaches to Illuminating Brain Structure and Dynamics

被引：91

作者：

Deisseroth, Karl ^{[1
,2
,5
,6
]}

Schnitzer, Mark J. ^{[3
,4
,5
,6
]}

机构：

[1] Stanford Univ, Dept Bioengn, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA

[3] Stanford Univ, Dept Biol, Stanford, CA 94305 USA

[4] Stanford Univ, Dept Appl Phys, Stanford, CA 94305 USA

[5] Stanford Univ, Howard Hughes Med Inst, Stanford, CA 94305 USA

[6] Stanford Univ, CNC Program, Stanford, CA 94305 USA

来源：

NEURON | 2013年 / 80卷 / 03期

基金：

美国国家科学基金会;

关键词：

CAENORHABDITIS-ELEGANS; FLUORESCENT PROTEIN; ACTION-POTENTIALS; NEURONS; HALORHODOPSIN; GENERATION; EXPRESSION; INDICATORS; MICROSCOPY; NANOSCOPY;

D O I：

10.1016/j.neuron.2013.10.032

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Historical milestones in neuroscience have come in diverse forms, ranging from the resolution of specific biological mysteries via creative experimentation to broad technological advances allowing neuroscientists to ask new kinds of questions. The continuous development of tools is driven with a special necessity by the complexity, fragility, and inaccessibility of intact nervous systems, such that inventive technique development and application drawing upon engineering and the applied sciences has long been essential to neuroscience. Here we highlight recent technological directions in neuroscience spurred by progress in optical, electrical, mechanical, chemical, and biological engineering. These research areas are poised for rapid growth and will likely be central to the practice of neuroscience well into the future.

引用

页码：568 / 577

页数：10

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