Safe endoscopic treatment of large colonic lipomas using endoscopic looping technique

Purpose. Colonic lipomas are benign, submucosal tumours that are usually asymptomatic. Typically, they are incidentally diagnosed during colonoscopy. Due to a low prevalence, the natural history of lipomas remains largely unknown. While large (>2 cm) lesions can cause symptoms and complications, their endoscopic treatment is not routinely recommended because of prior reports of it high rate of perforation. Methods. We used a standardized technique of polypectomy, using endoscopic looping to resect large colonic lipomas in 8 patients and followed their clinical outcomes. Results. The mean lipoma size was 3.9 +/- 1.2 cm (range 2.5-6 cm). No patient developed bleeding or perforation. On follow-up (mean = 13.5 months, range 2-29), there was one small residual lesion. Conclusion. Colonic lipomas larger than 2 cm can be safely and efficaciously removed using endoloop assisted polypectomy technique. Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.