Vitamin D for your patients with chronic hepatitis C?

被引：32

作者：

Rahman, Adeeb H. ^{[1
]}

Branch, Andrea D. ^{[1
]}

机构：

[1] Mt Sinai Sch Med, Icahn Med Inst 11 24, Div Liver Dis, New York, NY 10029 USA

来源：

JOURNAL OF HEPATOLOGY | 2013年 / 58卷 / 01期

关键词：

Hepatitis C; Vitamin D; 25(OH)D; 1,25(OH)(2)D; Inflammation; NECROSIS-FACTOR RECEPTORS; D SUPPLEMENTATION; LIVER-DISEASE; VIRUS; EXPRESSION; FIBROSIS; INTERFERON; OSTEOPOROSIS; CHEMOKINES; THERAPY;

D O I：

10.1016/j.jhep.2012.07.026

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Vitamin D is increasingly becoming recognized as an important physiological regulator with pleiotropic functions outside of its classical role in skeletal homeostasis. A growing body of clinical evidence highlights the prevalence and risks of vitamin D deficiency in patients suffering from chronic hepatitis C infection, and vitamin D supplementation has been proposed as an adjunct to current standards of care. This review considers the experimental evidence for the anti-inflammatory, antifibrotic and antiviral effects of vitamin D, and discusses the therapeutic potential of vitamin D supplementation to protect against liver disease progression and improve responses to treatment. (C) 2012 European Association for the Study of the Liver. Published by Elsevier Inc. All rights reserved.

引用

页码：184 / 189

页数：6

共 46 条

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