Fructose intolerance in children presenting with abdominal pain

被引:55
作者
Gomara, Robert E. [1 ]
Halata, Michael S. [1 ]
Newman, Leonard J. [1 ]
Bostwick, Howard E. [1 ]
Berezin, Stuart H. [1 ]
Cukaj, Lynnette [1 ]
See, Mary C. [1 ]
Medow, Marvin S. [1 ]
机构
[1] New York Med Coll, Dept Pediat, Div Pediat Gastroenterol & Nutr, Valhalla, NY 10595 USA
关键词
abdominal pain; carbohydrate malabsorption; fructose; hydrogen breath test;
D O I
10.1097/MPG.0b013e318166cbe4
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objectives: We determined the occurrence of fructose malabsorption in pediatric patients with previous diagnoses of abdominal pain caused by a functional bowel disorder, whether the restriction of fructose intake changes the reporting of symptoms, the role of fructose dosage, and the severity of resultant symptoms. Patients and Methods: We administered a fructose breath test to children presenting with persistent unexplained abdominal pain. Patients randomly received 1, 15, or 45 g fructose, and breath hydrogen was measured for 3 hours after ingestion. Test results were positive when breath hydrogen was 20 ppm greater than baseline and was accompanied by gastrointestinal symptoms. Results: A total of 32 patients was enrolled, and none of the 9 who received 1 g had positive results. Three of 10 who received 15 g and 8 of 13 who received 45 g had positive results. All patients with positive test results restricted their fructose intake. Among the group with positive results, 9 of 11 had rapid improvement of their gastrointestinal symptoms. After 2 months, all 9 patients continued to report improvement. Conclusions: We concluded that fructose malabsorption may be a significant problem in children and that management of dietary intake can be effective in reducing gastrointestinal symptoms.
引用
收藏
页码:303 / 308
页数:6
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