Optical axial scanning in confocal microscopy using an electrically tunable lens

被引：106

作者：

Jabbour, Joey M. ^{[1
]}

Malik, Bilal H. ^{[1
]}

Olsovsky, Cory ^{[1
]}

Cuenca, Rodrigo ^{[1
]}

Cheng, Shuna ^{[1
]}

Jo, Javier A. ^{[1
]}

Cheng, Yi-Shing Lisa ^{[2
]}

Wright, John M. ^{[2
]}

Maitland, Kristen C. ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Biomed Engn, College Stn, TX 77843 USA

[2] Texas A&M Univ, Baylor Coll Dent, Hlth Sci Ctr, Dept Diagnost Sci, Dallas, TX 75246 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2014年 / 5卷 / 02期

基金：

美国国家卫生研究院;

关键词：

ENDOMICROSCOPY; TISSUE; SYSTEM; FIELD;

D O I：

10.1364/BOE.5.000645

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper presents the use and characterization of an electrically focus tunable lens to perform axial scanning in a confocal microscope. Lateral and axial resolution are characterized over a >250 mu m axial scan range. Confocal microscopy using optical axial scanning is demonstrated in epithelial tissue and compared to traditional stage scanning. By enabling rapid axial scanning, minimizing motion artifacts, and reducing mechanical complexity, this technique has potential to enhance in vivo three-dimensional imaging in confocal endomicroscopy. (C) 2014 Optical Society of America

引用

页码：645 / 652

页数：8

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