Antimicrobial Activity of Ethylenediaminedisuccinate Metal Complexes

被引：7

作者：

Costa, Natalia J. S. ^{[1
]}

Bombardieri, Cintia R. ^{[2
]}

Kuribayashi, Juliana S. ^{[2
]}

de Camargo, Maristela M. ^{[2
]}

Andrade, Leandro H. ^{[1
]}

Kagohara, Edna ^{[1
]}

Esposito, Breno P. ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Chem, BR-05508000 Sao Paulo, Brazil

[2] Univ Sao Paulo, Inst Biomed Sci, BR-05508000 Sao Paulo, Brazil

来源：

CHEMISTRY & BIODIVERSITY | 2008年 / 5卷 / 10期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.1002/cbdv.200890196

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

It is shown that metal complexes of the biodegradable ligand ethylenediaminedisuccinic acid (edds) present antimicrobial activity towards fungi and bacteria. [Cd(edds)], in particular, is more toxic than free Cd2+ to Aspergillus niger, behaving as a 'Trojan Horse' in the facilitated delivery of the toxic metal into the fungus.

引用

页码：2156 / 2159

页数：4

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