Antimicrobial Activity of Ethylenediaminedisuccinate Metal Complexes

被引：7
作者：
Costa, Natalia J. S. [1 ]
Bombardieri, Cintia R. [2 ]
Kuribayashi, Juliana S. [2 ]
de Camargo, Maristela M. [2 ]
Andrade, Leandro H. [1 ]
Kagohara, Edna [1 ]
Esposito, Breno P. [1 ]
机构：
[1] Univ Sao Paulo, Inst Chem, BR-05508000 Sao Paulo, Brazil
[2] Univ Sao Paulo, Inst Biomed Sci, BR-05508000 Sao Paulo, Brazil
来源：
CHEMISTRY & BIODIVERSITY | 2008年 / 5卷 / 10期
基金：
巴西圣保罗研究基金会;
关键词：
D O I：
10.1002/cbdv.200890196
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
It is shown that metal complexes of the biodegradable ligand ethylenediaminedisuccinic acid (edds) present antimicrobial activity towards fungi and bacteria. [Cd(edds)], in particular, is more toxic than free Cd2+ to Aspergillus niger, behaving as a 'Trojan Horse' in the facilitated delivery of the toxic metal into the fungus.
引用
收藏
页码：2156 / 2159
页数：4
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