Nickel comb capacitors for real-time monitoring of cancer cell cultures

The work is devoted to the technology of biocompatible substrates with nickel electrodes for in vitro impedance cell culture studies. The legitimacy of this subject was tested by conducting measurements using a system based on the Electric Cell-Substrate Impedance Sensor method. A device for cell bioimpedance testing, made in thin-film technology, has been described. Parameters and applications of the material used for construction, which is commonly used nickel, are discussed. The results of preliminary studies on melanoma cancer cells from the A375 cell line were presented, during which the already used measurement matrices were used. An analysis of the observed changes and obtained results was carried out.