Studies of Cell Growth on TiO2 Nanotubes

被引：4

作者：

Barudin, Nur Hidayati Ahmad ^{[1
]}

Sreekantan, Srimala ^{[1
]}

Thong, Ong Ming ^{[2
]}

Lay, Lam Kit ^{[2
]}

机构：

[1] Univ Sains Malaysia, Sch Mat & Mineral Resources Engn, Nibong Tebal 14300, Penang, Malaysia

[2] Univ Sains Malaysia, Inst Res Mol Med INFORMM, George Town 11800, Malaysia

来源：

ADVANCED X-RAY CHARACTERIZATION TECHNIQUES | 2013年 / 620卷

关键词：

TiO2; nanotube; Anodization; Scanning electron microscope (SEM); Hs27; MCF-7;

D O I：

10.4028/www.scientific.net/AMR.620.325

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The in vitro cell response was investigated on flat Ti surface vs nanostructured TiO2 nanotube surface. The titanium dioxide nanotube layers were prepared by electrochemical anodization of Ti in ethylene glycol, 5 wt% NH4F and 1ml H2O2. The nanotube layered structure and morphology were characterized using X-ray diffraction (XRD) and field emission scanning electron microscopy (FESEM). The diameter and the length of the nanotubes are found to increase with anodization voltage. Hs27 and breast cancer cell line MCF-7 were used for cell interaction studies. Different surfaces of titanium show variation in term of growth and viability of cells. Different cell type also show different cellular responses to these surfaces. Titanium nanotube with tube diameter 90 nm promoted normal cell adherence and spreading but killed the cancer cells. The detail of the observation is discussed thoroughly in this paper.

引用

页码：325 / +

页数：2

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