Sexual function in patients with end-stage renal disease

Objective. Patients with chronic renal disease have sexual dysfunction to a great degree, but not many studies have been performed to study desire and sexual function in both men and women and the effects of active treatment for end-stage renal disease (ESRD). The aim of this study was to compare sexual function in patients with and without treatment for ESRD, where the patients served as their own controls. Material and methods. Sexual function was investigated in 117 patients with ESRD using a questionnaire in which the patients compared their sexual function before and after the onset of renal disease. Results. An overall decrease was seen in sexual desire (46%) and initiative (68%), and a pronounced decrease in sexual function, with regard to erection/lubrication (68%) and frequency of intercourse (64%). More than 50% of the patients admitted that the decrease in sexual function affected them considerably. Predialysis patients experienced less sexual dysfunction than patients undergoing active treatment. Women reported a minor ability to enjoy sex compared with men. No other gender differences in sexual dysfunction were identified in this study. No correlation between degree of sexual dysfunction and treatment modality or medication was found. Conclusion. A majority of the ESRD patients in this study report a substantial decrease in sexual desire, initiative and ability.