Correctness and response time distributions in the MemTrax continuous recognition task: Analysis of strategies and a reverse-exponential model

被引:7
作者
Ashford, J. Wesson [1 ,2 ]
Clifford, James O. O. [3 ]
Anand, Sulekha [4 ]
Bergeron, Michael F. F. [5 ]
Ashford, Curtis B. B. [6 ]
Bayley, Peter J. J. [1 ,2 ]
机构
[1] VA Palo Alto Hlth Care Syst, War Related Illness & Injury Study Ctr, Palo Alto, CA 94304 USA
[2] Stanford Univ, Dept Psychiat & Behav Sci, Palo Alto, CA 94305 USA
[3] Coll San Mateo, Dept Psychol, San Mateo, CA USA
[4] San Jose State Univ, Dept Biol Sci, San Jose, CA USA
[5] Univ Hartford, Dept Hlth Sci, Hartford, CT USA
[6] MemTrax LLC, Redwood City, CA USA
来源
FRONTIERS IN AGING NEUROSCIENCE | 2022年 / 14卷
关键词
Alzheimer's disease; cognition; cognitive impairment; dementia; episodic memory; memory; response time; recognition; MONTREAL COGNITIVE ASSESSMENT; DIFFUSION DECISION-MODEL; CHOICE REACTION-TIME; ALZHEIMERS-DISEASE; RETRIEVAL-PROCESSES; CONSTRUCT-VALIDITY; EPISODIC MEMORY; INFORMATION; DEMENTIA; ATTENTION;
D O I
10.3389/fnagi.2022.1005298
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
A critical issue in addressing medical conditions is measurement. Memory measurement is difficult, especially episodic memory, which is disrupted by many conditions. On-line computer testing can precisely measure and assess several memory functions. This study analyzed memory performances from a large group of anonymous, on-line participants using a continuous recognition task (CRT) implemented at . These analyses estimated ranges of acceptable performance and average response time (RT). For 344,165 presumed unique individuals completing the CRT a total of 602,272 times, data were stored on a server, including each correct response (HIT), Correct Rejection, and RT to the thousandth of a second. Responses were analyzed, distributions and relationships of these parameters were ascertained, and mean RTs were determined for each participant across the population. From 322,996 valid first tests, analysis of correctness showed that 63% of these tests achieved at least 45 correct (90%), 92% scored at or above 40 correct (80%), and 3% scored 35 correct (70%) or less. The distribution of RTs was skewed with 1% faster than 0.62 s, a median at 0.890 s, and 1% slower than 1.57 s. The RT distribution was best explained by a novel model, the reverse-exponential (RevEx) function. Increased RT speed was most closely associated with increased HIT accuracy. The MemTrax on-line memory test readily provides valid and reliable metrics for assessing individual episodic memory function that could have practical clinical utility for precise assessment of memory dysfunction in many conditions, including improvement or deterioration over time.
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页数:24
相关论文
共 102 条
[1]   The Shifted Wald Distribution for Response Time Data Analysis [J].
Anders, Royce ;
Alario, F. -Xavier ;
Van Maanen, Leendert .
PSYCHOLOGICAL METHODS, 2016, 21 (03) :309-327
[2]   Modeling the time-course of Alzheimer dementia. [J].
Ashford J.W. ;
Schmitt F.A. .
Current Psychiatry Reports, 2001, 3 (1) :20-28
[3]  
Ashford J.W., 2019, ETHNICITY DEMENTIAS
[4]  
Ashford J. W., 1998, COMPUT NEUR
[5]   Now is the Time to Improve Cognitive Screening and Assessment for Clinical and Research Advancement [J].
Ashford, J. Wesson ;
Schmitt, Frederick A. ;
Bergeron, Michael F. ;
Bayley, Peter J. ;
Clifford, James O. ;
Xu, Qun ;
Liu, Xiaolei ;
Zhou, Xianbo ;
Kumar, Vinod ;
Buschke, Herman ;
Dean, Margaret ;
Finkel, Sanford I. ;
Hyer, Lee ;
Perry, George .
JOURNAL OF ALZHEIMERS DISEASE, 2022, 87 (01) :305-315
[6]   A Computerized Continuous-Recognition Task for Measurement of Episodic Memory [J].
Ashford, J. Wesson ;
Tarpin-Bernard, Franck ;
Ashford, Curtis B. ;
Ashford, Miriam T. .
JOURNAL OF ALZHEIMERS DISEASE, 2019, 69 (02) :385-399
[7]   The Dichotomy of Alzheimer's Disease Pathology: Amyloid-β and Tau [J].
Ashford, J. Wesson .
JOURNAL OF ALZHEIMERS DISEASE, 2019, 68 (01) :77-83
[8]   Retrogenesis: A Model of Dementia Progression in Alzheimer's Disease Related to Neuroplasticity [J].
Ashford, J. Wesson ;
Bayley, Peter J. .
JOURNAL OF ALZHEIMERS DISEASE, 2013, 33 (04) :1191-1193
[9]   Measuring Memory in Large Group Settings Using a Continuous Recognition Test [J].
Ashford, J. Wesson ;
Gere, Emily ;
Bayley, Peter J. .
JOURNAL OF ALZHEIMERS DISEASE, 2011, 27 (04) :885-895
[10]   OCCIPITAL AND INFEROTEMPORAL RESPONSES TO VISUAL SIGNALS IN THE MONKEY [J].
ASHFORD, JW ;
FUSTER, JM .
EXPERIMENTAL NEUROLOGY, 1985, 90 (02) :444-466