Making Steady Progress on Direct Cardiac Reprogramming Toward Clinical Application

被引：12

作者：

Miki, Kenji ^{[1
]}

Yoshida, Yoshinori ^{[1
]}

Yamanaka, Shinya ^{[1
,2
]}

机构：

[1] Kyoto Univ, Ctr iPS Cell Res & Applicat, Kyoto 6068507, Japan

[2] Gladstone Inst Cardiovasc Dis, San Francisco, CA USA

来源：

CIRCULATION RESEARCH | 2013年 / 113卷 / 01期

关键词：

DEFINED FACTORS; TRANSCRIPTION FACTORS; FUNCTIONAL-NEURONS; HUMAN FIBROBLASTS; DIRECT CONVERSION; STEM-CELLS; CARDIOMYOCYTES; MICRORNA; HEARTS; INDUCTION;

D O I：

10.1161/CIRCRESAHA.113.301788

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A new report demonstrates direct cardiac reprogramming in human cells for the first time and points to the possibility of moving this technology toward clinical applications.

引用

页码：13 / 15

页数：3

共 50 条

[41] TBX20 Improves Contractility and Mitochondrial Function During Direct Human Cardiac Reprogramming [J].

Tang, Yawen ;

Aryal, Sajesan ;

Geng, Xiaoxiao ;

Zhou, Xinyue ;

Fast, Vladimir G. ;

Zhang, Jianyi ;

Lu, Rui ;

Zhou, Yang .

CIRCULATION, 2022, 146 (20) :1518-1536

[42] Direct cellular reprogramming for cardiac repair and regeneration [J].

Batty, Jonathan A. ;

Lima, Jose A. C., Jr. ;

Kunadian, Vijay .

EUROPEAN JOURNAL OF HEART FAILURE, 2016, 18 (02) :145-156

[43] Cardiac regeneration by direct reprogramming in this decade and beyond [J].

Hiroyuki Yamakawa ;

Masaki Ieda .

Inflammation and Regeneration, 41

[44] Direct cardiac reprogramming: basics and future challenges [J].

Andrianto Andrianto ;

Eka Prasetya Budi Mulia ;

Kevin Luke .

Molecular Biology Reports, 2023, 50 :865-871

[45] An Optimized Protocol for Human Direct Cardiac Reprogramming [J].

Garbutt, Tiffany A. ;

Zhou, Yang ;

Keepers, Benjamin ;

Liu, Jiandong ;

Qian, Li .

STAR PROTOCOLS, 2020, 1 (01)

[46] Direct Cardiac Reprogramming in the Age of Computational Biology [J].

Ambroise, Rachelle ;

Takasugi, Paige ;

Liu, Jiandong ;

Qian, Li .

JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE, 2024, 11 (09)

[47] Direct Cardiac Reprogramming for Cardiovascular Regeneration and Differentiation [J].

Sadahiro, Taketaro ;

Ieda, Masaki .

KEIO JOURNAL OF MEDICINE, 2020, 69 (03) :49-58

[48] Direct Cardiac Reprogramming with Engineered miRNA Scaffolds [J].

Muniyandi, Priyadharshni ;

Maekawa, Toru ;

Hanajiri, Tatsuro ;

Palaninathan, Vivekanandan .

CURRENT PHARMACEUTICAL DESIGN, 2020, 26 (34) :4285-4303

[49] Progress in direct reprogramming of dopaminergic cell replacement therapy [J].

Zheng, Yuan Yuan ;

Xu, Hui ;

Wang, Yue Si .

NEUROLOGICAL SCIENCES, 2024, 45 (03) :873-881

[50] Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming [J].

Zhou, Yang ;

Wang, Li ;

Vaseghi, Haley Ruth ;

Liu, Ziqing ;

Lu, Rui ;

Alimohamadi, Sahar ;

Yin, Chaoying ;

Fu, Ji-Dong ;

Wang, Greg G. ;

Liu, Jiandong ;

Qian, Li .

CELL STEM CELL, 2016, 18 (03) :382-395

← 1 2 3 4 5 →