p53 expression in oral precancer and cancer

被引：20

作者：

Rich, AM ^{[1
]}

Kerdpon, D ^{[1
]}

Reade, PC ^{[1
]}

机构：

[1] Univ Otago, Sch Dent, Dept Stomatol, Dunedin, New Zealand

来源：

AUSTRALIAN DENTAL JOURNAL | 1999年 / 44卷 / 02期

关键词：

p53; expression; oral epithelial dysplasia; oral squamous cell carcinoma;

D O I：

10.1111/j.1834-7819.1999.tb00209.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Expression of the p53 tumour suppressor gene is a frequent finding in human malignancies, including oral cancer, and it has been detected in some potentially malignant lesions. The results of the present project showed that 35 of the 41 (85 per cent) oral mucosal lesions with histological evidence of epithelial dysplasia expressed p53, but the presence or absence of p53 staining could not be used to predict the outcome of potentially malignant oral mucosal lesions.

引用

页码：103 / 105

页数：3

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