Cancer immunotherapy Re-programming cells of the innate and adaptive immune systems

被引：9

作者：

Manjili, Masoud H. ^{[1
]}

Payne, Kyle K. ^{[1
]}

机构：

[1] Virginia Commonwealth Univ, Dept Microbiol & Immunol, Massey Canc Ctr, Richmond, VA 23298 USA

来源：

ONCOIMMUNOLOGY | 2012年 / 1卷 / 02期

关键词：

NKT cells; immunotherapy; myeloid-derived suppressor cells; adoptive cellular therapy; common gamma chain cytokines; breast cancer; TUMOR-SENSITIZED LYMPHOCYTES; ACTIVATED NKT CELLS; CD8(+) T-CELLS; SUPPRESSOR-CELLS; DENDRITIC CELLS; IMMUNOREGULATORY AXIS; ANTINEOPLASTIC AGENT; PROGNOSTIC-FACTOR; BREAST-CANCER; IFN-GAMMA;

D O I：

10.4161/onci.1.2.18113

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cancers utilize multiple mechanisms to overcome immune responses. Emerging evidence suggest that immunotherapy of cancer should focus on inducing and re-programming cells of the innate and adaptive immune systems rather than focusing solely on T cells. Recently, we have shown that such a multifaceted approach can improve immunotherapy of breast cancer.

引用

页码：201 / 204

页数：4

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