HLODs remain powerful tools for detection of linkage in the presence of genetic heterogeneity

被引：35

作者：

Hodge, SE

Vieland, VJ

Greenberg, DA

机构：

[1] Columbia Univ, Dept Psychiat, NYSPI, Unit 24, New York, NY 10032 USA

[2] Columbia Univ, Dept Biostat, Div Stat Genet, New York, NY USA

[3] New York State Psychiat Inst & Hosp, Div Clin Genet Epidemiol, New York, NY 10032 USA

[4] Columbia Univ, Genome Ctr, New York, NY USA

[5] Univ Iowa, Coll Publ Hlth, Dept Biostat, Div Stat Genet, Iowa City, IA USA

[6] Univ Iowa, Coll Med, Dept Psychiat, Iowa City, IA 52242 USA

来源：

AMERICAN JOURNAL OF HUMAN GENETICS | 2002年 / 70卷 / 02期

关键词：

D O I：

10.1086/338923

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

收藏

页码：556 / 558

页数：3

相关论文

共 19 条

[1] Direct power comparisons between simple LOD scores and NPL scores for linkage analysis in complex diseases
Abreu, PC
Greenberg, DA
Hodge, SE
[J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 65 (03) : 847 - 857
[2] ABREU PC, IN PRESS GENET EPIDE
[3] Further evidence for the increased power of LOD scores compared with nonparametric methods
Durner, M
Vieland, VJ
Greenberg, DA
[J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 64 (01) : 281 - 289
[4] DURNER M, 1992, AM J HUM GENET, V51, P859
[5] EFFECT OF HETEROGENEITY AND ASSUMED MODE OF INHERITANCE ON LOD SCORES
DURNER, M
GREENBERG, DA
[J]. AMERICAN JOURNAL OF MEDICAL GENETICS, 1992, 42 (03): : 271 - 275
[6] DISTRIBUTION OF THE ADMIXTURE TEST FOR THE DETECTION OF LINKAGE UNDER HETEROGENEITY
FARAWAY, JJ
[J]. GENETIC EPIDEMIOLOGY, 1993, 10 (01) : 75 - 83
[7] DETECTION OF LINKAGE UNDER HETEROGENEITY - COMPARISON OF THE 2-LOCUS VS ADMIXTURE MODELS
GOLDIN, LR
[J]. GENETIC EPIDEMIOLOGY, 1992, 9 (01) : 61 - 66
[8] GOLDIN LR, 1993, AM J HUM GENET, V53, P908
[9] Determining trait locus position from multipoint analysis: Accuracy and power of three different statistics
Greenberg, DA
Abreu, PC
[J]. GENETIC EPIDEMIOLOGY, 2001, 21 (04) : 299 - 314
[10] HODGE SE, 1983, AM J HUM GENET, V35, P1139