The crystal structure of 8-chloro-7-ethyl-1,3-dimethyl-1H-purine-2,6( 3H,7H)-dione, C9H11ClN4O2

被引:1
|
作者
Ali, Syed Saeed [1 ,2 ]
Al-Obaid, Abdulrahman M. [1 ]
Hosten, Eric C. [3 ]
Bari, Ahmed [1 ,2 ]
机构
[1] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, POB 2457, Riyadh 11451, Saudi Arabia
[2] King Saud Univ, Coll Pharm, Res Ctr, POB 2457, Riyadh 11451, Saudi Arabia
[3] Nelson Mandela Univ, Dept Chem, POB 77000, ZA-6031 Port Elizabeth, South Africa
关键词
D O I
10.1515/ncrs-2017-0314
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
C9H11ClN4O2, orthorhombic, Pbca (no. 61), a=8.9735(4) angstrom, b=12.2946(7) angstrom, c=19.3751(11) angstrom, V=2137.6(2) angstrom(3), Z = 8, R-gt(F)= 0.0355, wR(ref)(F2)=0.1087, T = 200(2) K.
引用
收藏
页码:317 / 318
页数:2
相关论文
共 50 条
  • [1] 8-(2-Hydroxyphenyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
    Booysen, Irvin
    Hlela, Thulani
    Ismail, Muhammed
    Gerber, Thomas
    Hosten, Eric
    Betz, Richard
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2347 - U374
  • [2] 1,3-Dibutyl-1H-purine-2,6(3H,7H)-dione
    Jing, Zuo-Liang
    Yu, Ming
    Chen, Xin
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O3996 - U2535
  • [3] 8-Chloro-7-(2,6-dichlorobenzyl)-1,3-dimethyl-7H-purine-2,6(1H,3H)-dione
    Belyakov, S
    Alksnis, E
    Muravenko, V
    Lukevics, E
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2005, 61 : O63 - O64
  • [4] Structure-5-HT Receptor Affinity Relationship in a New Group of 7-Arylpiperazynylalkyl and 7-Tetrahydroisoquinolinylalkyl Derivatives of 8-Amino-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
    Zmudzki, Pawel
    Chlon-Rzepa, Grazyna
    Bojarski, Andrzej J.
    Zygmunt, Malgorzata
    Kazek, Grzegorz
    Mordyl, Barbara
    Pawlowski, Maciej
    ARCHIV DER PHARMAZIE, 2015, 348 (04) : 229 - 241
  • [5] Design, synthesis and in silico insights of new 7, 8-disubstituted-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione derivatives with potent anticancer and multi-kinase inhibitory activities
    Mohamed, Abdalla R.
    Kerdawy, Ahmed M. El
    George, Riham F.
    Georgey, Hanan H.
    Gawad, Nagwa M. Abdel
    BIOORGANIC CHEMISTRY, 2021, 107
  • [6] Synthetic access of new 6-purineselenyl and 8-(1,3,4-thiadiazolyl)-7-benzyl-1, 3-dimethyl-1H-purine-2,6-(3H,7H)-dione derivatives
    Gobouri, Adil A. H.
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2020, 195 (09) : 774 - 778
  • [7] Synthesis and Antidepressant Properties of 3-Methyl-7-(1,1-Dioxothietan-3-YL)-8-Cyclohexylamino-1-Ethyl-1H-Purine-2,6(3H,7H)-Dione
    F. A. Khaliullin
    Yu. V. Shabalina
    G. G. Davlyatova
    L. A. Valeeva
    Pharmaceutical Chemistry Journal, 2018, 51 : 1049 - 1052
  • [8] Synthesis and Antidepressant Properties of 3-Methyl-7-(1,1-Dioxothietan-3-YL)-8-Cyclohexylamino-1-Ethyl-1H-Purine-2,6(3H,7H)-Dione
    Khaliullin, F. A.
    Shabalina, Yu. V.
    Davlyatova, G. G.
    Valeeva, L. A.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2018, 51 (12) : 1049 - 1052
  • [9] MOLECULAR DOCKING STUDY ON 1-(3-(4-BENZYLPIPERAZIN-1-YL)PROPYL)-3,7-DIMETHYL-1H-PURINE-2,6(3H,7H)-DIONE AS AN ACETYLCHOLINESTERASE INHIBITOR
    Hristova, Maria
    Atanasova, Mariyana
    Valkova, Iva
    Andonova, Lilya
    Doytchinova, Irini
    Zlatkov, Alexander
    CBU INTERNATIONAL CONFERENCE PROCEEDINGS 2018: INNOVATIONS IN SCIENCE AND EDUCATION, 2018, 6 : 898 - 903
  • [10] Structure-5-HT/D2 Receptor Affinity Relationship in a New Group of 1-Arylpiperazynylalkyl Derivatives of 8-Dialkylamino-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione
    Zmudzki, Pawel
    Satala, Grzegorz
    Chlon-Rzepa, Grazyna
    Bojarski, Andrzej J.
    Kazek, Grzegorz
    Siwek, Agata
    Grybos, Anna
    Gluch-Lutwin, Monika
    Wesolowska, Anna
    Pawlowski, Maciej
    ARCHIV DER PHARMAZIE, 2016, 349 (10) : 774 - 784