A case of synchronous bilateral testicular seminoma

被引：1

作者：

Resnick, Matthew J. ^{[1
]}

Canter, Daniel ^{[1
]}

Brucker, Benjamin M. ^{[1
]}

Kutikov, Alexander ^{[1
]}

Guzzo, Thomas J. ^{[1
]}

Wein, Alan J. ^{[1
]}

机构：

[1] Hosp Univ Penn, Philadelphia, PA 19104 USA

来源：

NATURE CLINICAL PRACTICE UROLOGY | 2008年 / 5卷 / 07期

关键词：

bilateral; seminoma; synchronous; testicular neoplasia;

D O I：

10.1038/ncpuro1133

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background A previously healthy 51-year-old man with two children sustained a minor testicular trauma and subsequently sought medical care for persistent discomfort. Investigations Physical examination, scrotal ultrasonography, Doppler ultrasound evaluation of testicular blood flow, scrotal MRI, measurement of serum tumor markers and testosterone levels, CT of the chest, abdomen and pelvis, intraoperative frozen section analysis and final pathologic analysis. Diagnosis Bilateral testicular seminoma (clinical stage I). Management The patient initially underwent radical left orchiectomy with intraoperative frozen section analysis, which returned equivocal results. Final pathologic analysis revealed a 2.5 cm left testicular seminoma without vascular invasion. After careful discussion, he ultimately underwent radical right orchiectomy; pathologic analysis revealed a 2.7 cm right seminoma with vascular invasion. Testosterone replacement therapy was initiated. After further discussion, the patient elected to undergo adjuvant abdominal radiotherapy to a total of 25 Gy. The patient showed no evidence of disease over a post-treatment follow-up period of 24 months.

引用

页码：397 / 401

页数：5

共 16 条

[1] Risk-adapted management for patients with clinical stage I seminoma:: The second Spanish germ cell cancer cooperative group study [J].