A Phase I Study of Single-Agent Inotuzumab Ozogamicin in Pediatric CD22-Positive Relapsed/Refractory Acute Lymphoblastic Leukemia: Preliminary Results of the ITCC-059 Study

被引:5
作者
Brivio, Erica [1 ]
Lopez-Yurda, Marta [1 ,2 ,3 ]
Ownes, Cormac [4 ]
Diaz de Heredia, Cristina [5 ]
Bielorai, Bella [6 ]
Rossig, Claudia [7 ]
Van der Velden, Vincent [8 ]
Ammerlaan, Anneke C. J. [1 ]
van der Sluis, Inge M. [1 ]
Den Boer, Monique L. [1 ,2 ]
Chen, Ying [9 ]
Sleight, Barbara [10 ]
Brethon, Benoit [11 ]
Nysom, Karsten [12 ]
Stary, Jan [13 ]
Ora, Ingrid [14 ]
Chen-Santel, Christiane [15 ]
Vinti, Luciana [16 ]
Locatelli, Franco [17 ]
Zwaan, Christian Michel [1 ,2 ]
机构
[1] Princess Maxima Ctr Pediat Oncol, Utrecht, Netherlands
[2] Erasmus MC, Dept Pediat Oncol Hematol, Sophia Childrens Hosp, Rotterdam, Netherlands
[3] Netherlands Canc Inst, Dept Biometr, Amsterdam, Netherlands
[4] Our Ladys Childrens Hosp Crumlin, Dublin, Ireland
[5] Hosp Univ Vall dHebron Vall dHebron, Pediat Oncol & Hematol Dept, Barcelona, Spain
[6] Sheba Med Ctr, Div Pediat Hematol & Oncol, Ramat Gan, Israel
[7] Univ Childrens Hosp Muenster, Pediat Hematol & Oncol, Munster, Germany
[8] Erasmus MC, Dept Immunol, Rotterdam, Netherlands
[9] Pfizer Inc, Clin Pharmacol, San Diego, CA USA
[10] Pfizer Inc, Groton, CT 06340 USA
[11] Univ Paris, Robert Debre Hosp, AP HP, Dept Pediat Hematol & Immunol, Paris, France
[12] Rigshosp, Copenhagen, Denmark
[13] Univ Hosp Motol, Dept Pediat Hematol & Oncol, Prague, Czech Republic
[14] Karolinska Univ Hosp, Pediat Oncol Unit, Stockholm, Sweden
[15] Charite Univ Med Berlin, Div Hematol & Oncol, Dept Pediat, Berlin, Germany
[16] IRCCS Bambino Gesu Childrens Hosp, Dept Pediat Hematol Oncol Cell & Gene Therapy, Rome, Italy
[17] Univ Rome Sapienza, Dept Hematol Oncol & transfus Med, Osped Pediat Bambino Gesu, Rome, Italy
关键词
D O I
10.1182/blood-2019-122411
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2629
引用
收藏
页数:5
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