An Update on Diabetic Women Obstetrical Outcomes Linked to Preconception and Pregnancy Glycemic Profile: A Systematic Literature Review

被引：31

作者：

Gizzo, Salvatore ^{[1
]}

Patrelli, Tito Silvio ^{[2
]}

Rossanese, Marta ^{[1
]}

Noventa, Marco ^{[1
]}

Berretta, Roberto ^{[2
,3
]}

Di Gangi, Stefania ^{[1
]}

Bertin, Martina ^{[1
]}

Gangemi, Michele ^{[1
]}

Nardelli, Giovanni Battista ^{[1
]}

机构：

[1] Univ Padua, Dept Woman & Child Hlth, I-35128 Padua, Italy

[2] Univ Parma, Dept Surg Sci, I-43100 Parma, Italy

[3] UOC Ginecol & Ostetricia, Dipartimento Sci Chirurg, I-43100 Parma, Italy

来源：

SCIENTIFIC WORLD JOURNAL | 2013年

关键词：

CONGENITAL-MALFORMATIONS; INDUCED HYPERTENSION; INSULIN-RESISTANCE; TYPE-1; RISK; MELLITUS; OBESITY; PREECLAMPSIA; POPULATION; STILLBIRTH;

D O I：

10.1155/2013/254901

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Women with type 2 diabetes were less likely to have diabetes related complications than women with type 1. Women with type 1 diabetes had a high prepregnancy care and showed a worse glycemic control than women with type 2 both in the preconception period and during pregnancy. Obstetrical outcomes showed that preeclampsia and stillbirth rate is almost doubled in type 1 patients while perinatal deaths and SGA importantly increased in type 2 diabetes. In modern obstetrical care it is mandatory to maintain glucose levels as close to normal as possible particularly in diabetic population. HbA1C no higher than 6% before pregnancy and during the first trimester seems to decrease the risk of adverse obstetrical outcomes. Both the preconceptional counseling and glycemic profile optimization represent a fundamental step to improve pregnancy outcomes in women with preexisting diabetes. A systematic approach to family planning and the availability of preconception care for all diabetic women who desire pregnancy could be an essential step for diabetic management program.

引用

页数：9

共 39 条

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