Enantioselective recognition of carbamate-type molecular tweezers derived from deoxycholic acid for amino acid methyl esters

被引：0

作者：

Xue, CH ^{[1
]}

Mu, QM ^{[1
]}

Chen, SH ^{[1
]}

机构：

[1] Sichuan Univ, Fac Chem, Chengdu 610064, Peoples R China

来源：

ACTA CHIMICA SINICA | 2002年 / 60卷 / 02期

关键词：

molecular tweezers; deoxycholic acid; amino acid methyl ester; enantioselective recognition;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New chiral molecular tweezers 1 similar to 4 have been synthesized by using deoxycholic acid as a spacer to bridge the different aromatic amines. Their structures were confirmed by IR, H-1 NMR and elemental analysis. Enantioselective recognition properties of these molecular tweezers for amino acid methyl esters have been investigated by UV-vis spectra titration in CHCl3 at 25 degreesC. The results indicate that molecular tweezers 1 - 4 not only recognize all amino acid methyl esters examined but also possess higher selectivity for D-amino acid methyl esters. The recognition ability and selectivity axe discussed from the viewpoint of the size/shape-fit and geometrical complementary relationship between the molecular tweezers and amino acid methyl esters.

引用

页码：355 / 359

页数：5

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