Pathogenomics

被引:4
作者
Crossman, L [1 ]
Cerdeño-Tárraga, A [1 ]
Bentley, S [1 ]
Parkhill, J [1 ]
机构
[1] Sanger Inst, Cambridge CB10 1SA, England
关键词
D O I
10.1038/nrmicro778
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The genomes described this month reflect the overall historical bias of microbial genomics towards pathogenic bacteria. Although the balance is now being redressed to some extent, especially through the study of extremophiles, it is still the case that the opportunities provided by genomic studies are primarily taken up by those who study bacterial pathogenicity. This part of the field is, however, being broadened by including the study of pathogens of animals, insects and plants alongside those that afflict humans.
引用
收藏
页码:176 / 177
页数:2
相关论文
共 12 条
[1]   Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori [J].
Alm, RA ;
Ling, LSL ;
Moir, DT ;
King, BL ;
Brown, ED ;
Doig, PC ;
Smith, DR ;
Noonan, B ;
Guild, BC ;
deJonge, BL ;
Carmel, G ;
Tummino, PJ ;
Caruso, A ;
Uria-Nickelsen, M ;
Mills, DM ;
Ives, C ;
Gibson, R ;
Merberg, D ;
Mills, SD ;
Jiang, Q ;
Taylor, DE ;
Vovis, GF ;
Trost, TJ .
NATURE, 1999, 397 (6715) :176-180
[2]   Complete genome sequence and analysis of Wolinella succinogenes [J].
Baar, C ;
Eppinger, M ;
Raddatz, G ;
Simon, J ;
Lanz, C ;
Klimmek, O ;
Nandakumar, R ;
Gross, R ;
Rosinus, A ;
Keller, H ;
Jagtap, P ;
Linke, B ;
Meyer, F ;
Lederer, H ;
Schuster, SC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (20) :11690-11695
[3]   Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei [J].
Bentley, SD ;
Maiwald, M ;
Murphy, LD ;
Pallen, MJ ;
Yeats, CA ;
Dover, LG ;
Norbertczak, HT ;
Besra, GS ;
Quail, MA ;
Harris, DE ;
von Herbay, A ;
Goble, A ;
Rutter, S ;
Squares, R ;
Squares, S ;
Barrell, BG ;
Parkhill, J ;
Relman, DA .
LANCET, 2003, 361 (9358) :637-644
[4]  
CERDENOTARRAGA AM, NUCL ACIDS RES
[5]   G+C3 structuring along the genome:: A common feature in prokaryotes [J].
Daubin, V ;
Perrière, G .
MOLECULAR BIOLOGY AND EVOLUTION, 2003, 20 (04) :471-483
[6]  
DUCHAUD E, NAT BIOTECHNOL
[7]   Localization of Tropheryma whippelii rRNA in tissues from patients with Whipple's disease [J].
Fredricks, DN ;
Relman, DA .
JOURNAL OF INFECTIOUS DISEASES, 2001, 183 (08) :1229-1237
[8]   The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences [J].
Parkhill, J ;
Wren, BW ;
Mungall, K ;
Ketley, JM ;
Churcher, C ;
Basham, D ;
Chillingworth, T ;
Davies, RM ;
Feltwell, T ;
Holroyd, S ;
Jagels, K ;
Karlyshev, AV ;
Moule, S ;
Pallen, MJ ;
Penn, CW ;
Quail, MA ;
Rajandream, MA ;
Rutherford, KM ;
van Vliet, AHM ;
Whitehead, S ;
Barrell, BG .
NATURE, 2000, 403 (6770) :665-668
[9]   Genome sequence of Yersinia pestis, the causative agent of plague [J].
Parkhill, J ;
Wren, BW ;
Thomson, NR ;
Titball, RW ;
Holden, MTG ;
Prentice, MB ;
Sebaihia, M ;
James, KD ;
Churcher, C ;
Mungall, KL ;
Baker, S ;
Basham, D ;
Bentley, SD ;
Brooks, K ;
Cerdeño-Tárraga, AM ;
Chillingworth, T ;
Cronin, A ;
Davies, RM ;
Davis, P ;
Dougan, G ;
Feltwell, T ;
Hamlin, N ;
Holroyd, S ;
Jagels, K ;
Karlyshev, AV ;
Leather, S ;
Moule, S ;
Oyston, PCF ;
Quail, M ;
Rutherford, K ;
Simmonds, M ;
Skelton, J ;
Stevens, K ;
Whitehead, S ;
Barrell, BG .
NATURE, 2001, 413 (6855) :523-527
[10]   Tropheryma whipplei twist:: A human pathogenic Actinobacteria with a reduced genome [J].
Raoult, D ;
Ogata, H ;
Audic, S ;
Robert, C ;
Suhre, K ;
Drancourt, M ;
Claverie, JM .
GENOME RESEARCH, 2003, 13 (08) :1800-1809