Elastomeric recombinant protein-based biomaterials

被引：76

作者：

Annabi, Nasim ^{[1
,2
,3
]}

Mithieux, Suzanne M. ^{[4
]}

Camci-Unal, Gulden ^{[1
,2
]}

Dokmeci, Mehmet R. ^{[1
,2
]}

Weiss, Anthony S. ^{[4
,5
,6
]}

Khademhosseini, Ali ^{[1
,2
,3
]}

机构：

[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Ctr Biomed Engn,Dept Med, Boston, MA 02139 USA

[2] MIT, Harvard MIT Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[3] Harvard Univ, Wyss Inst Biol Inspired Engn, Cambridge, MA 02139 USA

[4] Univ Sydney, Sch Mol Biosci, Sydney, NSW 2006, Australia

[5] Univ Sydney, Bosch Inst, Sydney, NSW 2006, Australia

[6] Univ Sydney, Charles Perkins Ctr, Sydney, NSW 2006, Australia

来源：

BIOCHEMICAL ENGINEERING JOURNAL | 2013年 / 77卷

基金：

美国国家卫生研究院; 美国国家科学基金会; 英国医学研究理事会; 澳大利亚研究理事会;

关键词：

Elastomer; Tropoelastin; Elastin-like polypeptides; Biomaterials; Elasticity; ELASTIN-LIKE POLYPEPTIDE; CROSS-LINKING; MECHANICAL-PROPERTIES; EXTRACELLULAR-MATRIX; HUMAN TROPOELASTIN; ESCHERICHIA-COLI; BLOCK-COPOLYMERS; BINDING PROTEIN; FIBER FORMATION; VASCULAR GRAFT;

D O I：

10.1016/j.bej.2013.05.006

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Elastomeric protein-based biomaterials, produced from elastin derivatives, are widely investigated as promising tissue engineering scaffolds due to their remarkable properties including substantial extensibility, long-term stability, self-assembly, high resilience upon stretching, low energy loss, and excellent biological activity. These elastomers are processed from different sources of soluble elastin such as animal-derived soluble elastin, recombinant human tropoelastin, and elastin-like polypeptides into various forms including three dimensional (3D) porous hydrogels, elastomeric films, and fibrous electrospun scaffolds. Elastin-based biomaterials have shown great potential for the engineering of elastic tissues such as skin, lung and vasculature. In this review, the synthesis and properties of various elastin-based elastomers with their applications in tissue engineering are described. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：110 / 118

页数：9

共 110 条

[51]

MacEwan S.R., 2012, PEPT SCI, V94, P60

[52] TOTAL SYNTHESIS AND EXPRESSION IN ESCHERICHIA-COLI OF A GENE ENCODING HUMAN TROPOELASTIN [J].

MARTIN, SL ;

VRHOVSKI, B ;

WEISS, AS .

GENE, 1995, 154 (02) :159-166

[53] A hypothesis about a mechanism for the programming of blood pressure and vascular disease in early life [J].

Martyn, CN ;

Greenwald, SE .

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2001, 28 (11) :948-951

[54] Structure and Activity of Aspergillus nidulans Copper Amine Oxidase [J].

McGrath, Aaron P. ;

Mithieux, Suzanne M. ;

Collyer, Charles A. ;

Bakhuis, Janny G. ;

van den Berg, Marco ;

Sein, Arjen ;

Heinz, Andrea ;

Schmelzer, Christian ;

Weiss, Anthony S. ;

Guss, J. Mitchell .

BIOCHEMISTRY, 2011, 50 (25) :5718-5730

[55] Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair [J].

McHale, MK ;

Setton, LA ;

Chilkoti, A .

TISSUE ENGINEERING, 2005, 11 (11-12) :1768-1779

[56] Mechanical property characterization of electrospun recombinant human tropoelastin for vascular graft biomaterials [J].

McKenna, Kathryn A. ;

Hinds, Monica T. ;

Sarao, Rebecca C. ;

Wu, Ping-Cheng ;

Maslen, Cheryl L. ;

Glanville, Robert W. ;

Babcock, Darcie ;

Gregory, Kenton W. .

ACTA BIOMATERIALIA, 2012, 8 (01) :225-233

[57] High-resolution topographic imaging of environmentally responsive, elastin-mimetic hydrogels [J].

McMillan, RA ;

Caran, KL ;

Apkarian, RP ;

Conticello, VP .

MACROMOLECULES, 1999, 32 (26) :9067-9070

[58] Synthesis and characterization of elastin-mimetic protein gels derived from a well-defined polypeptide precursor [J].

McMillan, RA ;

Conticello, VP .

MACROMOLECULES, 2000, 33 (13) :4809-4821

[59] Rapid assembly of synthetic genes encoding protein polymers [J].

McMillan, RA ;

Lee, TAT ;

Conticello, VP .

MACROMOLECULES, 1999, 32 (11) :3643-3648

[60] Product purification by reversible phase transition following Escherichia coli expression of genes encoding up to 251 repeats of the elastomeric pentapeptide GVGVP [J].

McPherson, DT ;

Xu, J ;

Urry, DW .

PROTEIN EXPRESSION AND PURIFICATION, 1996, 7 (01) :51-57

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