Synthesis of oxazolinyl aziridines

被引：31
作者：
Florio, S
Troisi, L
Capriati, V
Ingrosso, G
机构：
[1] Univ Bari, CNR, Ctr Studio Metodol Innovat Sintesi Organ, Dipartimento Farmacochim, I-70125 Bari, Italy
[2] Univ Lecce, Dipartimento Biol, I-73100 Lecce, Italy
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 33期
关键词：
lithiation; aziridinyllithiums; oxazolinyl aziridines;
D O I：
10.1016/S0040-4039(99)01212-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Aziridinyllithiums 4a and 4b, which are stable at low temperature, can be generated by deprotonation of 3a and 3b. Oxazolinyl aziridines 5a-j and 6a-b have been prepared by the reaction of oxazolinyl aziridinyllithiums 4a and 4b with electrophiles. Aziridines 6c and 6d were, instead, synthesized by a Darzens-like reaction from 2-(1-chloroethyl)-2-oxazoline 1b. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：6101 / 6104
页数：4
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