Current treatments of vulvar cancer

被引:0
作者
Mathevet, P. [1 ]
机构
[1] Univ Lyon 1, Hop Femme Mere Enfant, Gynecol Serv, F-69677 Bron, France
来源
JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION | 2012年 / 41卷 / 06期
关键词
Vulvar cancer; Vulvectomy; Sentinel node; Vulvar radiotherapy; SQUAMOUS-CELL CARCINOMA; SENTINEL NODE PROCEDURE; RADIATION-THERAPY; ACCURACY; BIOPSY; LYMPHADENECTOMY; RESECTION;
D O I
10.1016/j.jgyn.2012.03.011
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Vulvar cancers are rare genital tumors. Their etiology is better understood. The management of these tumors has benefitted from recent therapeutic advances that decrease the morbidity of the treatments. Surgery is still the major curative option. But the limitation of the vulvar resections and the development of the sentinel-node technique have led to lower surgical morbidity and sequellas without increasing the risk of recurrence. Also improvements in radiotherapeutic treatment have been observed. Currently radiotherapy is realized in association with surgery in case of presence of risk factors of recurrence, or in place of surgery when this treatment is not possible or is too much aggressive. Morbidity of radiotherapy has largely decreased and association with chemotherapy leads probably to increased efficacy. (c) 2012 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:519 / 525
页数:7
相关论文
共 32 条
[1]   Economic burden of HPV-related cancers in France [J].
Borget, I. ;
Abramowitz, L. ;
Mathevet, P. .
VACCINE, 2011, 29 (32) :5245-5249
[2]   Margin distance and other clinico-pathologic prognostic factors in vulvar carcinoma: A multivariate analysis [J].
Chan, John K. ;
Sugiyama, Valerie ;
Pham, Huyen ;
Gu, Mai ;
Rutgers, Joanne ;
Osann, Kathryn ;
Cheung, Michael K. ;
Berman, Michael L. ;
DiSaia, Philip J. .
GYNECOLOGIC ONCOLOGY, 2007, 104 (03) :636-641
[3]   A CLASSIFICATION OF FASCIO-CUTANEOUS FLAPS ACCORDING TO THEIR PATTERNS OF VASCULARIZATION [J].
CORMACK, GC ;
LAMBERTY, BGH .
BRITISH JOURNAL OF PLASTIC SURGERY, 1984, 37 (01) :80-87
[4]   The accuracy of the sentinel node procedure after excision biopsy in squamous cell carcinoma of the vulva [J].
Crosbie, Emma J. ;
Winter-Roach, Brett ;
Sengupta, Partha ;
Sikand, Kanwal A. ;
Carrington, Bernadette ;
Murby, Brian ;
Slade, Richard J. .
SURGICAL ONCOLOGY-OXFORD, 2010, 19 (04) :E150-E154
[5]   The management of vulval cancer [J].
Crosbie, Emma J. ;
Slade, Richard J. ;
Ahmed, Ahmed S. .
CANCER TREATMENT REVIEWS, 2009, 35 (07) :533-539
[6]   Surgery and radiotherapy in vulvar cancer [J].
de Hullu, J. A. ;
van der Zee, A. G. J. .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2006, 60 (01) :38-58
[7]   Vulvar carcinoma - The price of less radical surgery [J].
de Hullu, JA ;
Hollema, H ;
Lolkema, S ;
Boezen, M ;
Boonstra, H ;
Burger, MPM ;
Aalders, JG ;
Mourits, MJE ;
van der Zee, AGJ .
CANCER, 2002, 95 (11) :2331-2338
[8]   ALTERNATE APPROACH TO EARLY CANCER OF THE VULVA [J].
DISAIA, PJ ;
CREASMAN, WT ;
RICH, WM .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1979, 133 (07) :825-832
[9]   Neoadjuvant Chemotherapy in Advanced Vulvar Cancer [J].
Domingues, Ana Patricia ;
Mota, Fernando ;
Durao, Marta ;
Frutuoso, Cristina ;
Amaral, Natalia ;
de Oliveira, Carlos Freire .
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2010, 20 (02) :294-298
[10]  
Douay-Hauser N, 2008, B CANCER, V95, P701, DOI 10.1684/bdc.2008.0642