A new boronic acid based fluorescent reporter for catechol

被引：38

作者：

Wu, Zhongyu ^{[1
]}

Li, Minyong ^{[1
]}

Fang, Hao ^{[1
]}

Wang, Binghe ^{[2
]}

机构：

[1] Shandong Univ, Sch Pharm, Minist Educ, Dept Med Chem,Key Lab Chem Biol, Jinan 250012, Peoples R China

[2] Gerogia State Univ, Dept Chem, Atlanta, GA 30303 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2012年 / 22卷 / 23期

基金：

中国国家自然科学基金;

关键词：

Boronic acid; Catechol detection; Chemosensor; Fluorescent reporter; ELECTROCATALYTIC OXIDATION; SELECTIVE DETERMINATION; ASCORBIC-ACID; DOPAMINE; INFLAMMATION; AGGREGATION; RECOGNITION; SENSOR; AMINE; WATER;

D O I：

10.1016/j.bmcl.2012.09.060

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Catechol skeleton widely exists in natural products and bioactive substances. Fluorescent reporters which could recognize catechol are very promising for the construction of chemosensors to detect catechol and its derivatives in biological environment. Herein, we reported a novel catechol reporter, 2-(4-boronophenyl)quinoline-4-carboxylic acid, which exhibits significant fluorescent property changes upon binding catechol containing molecules in an aqueous solution. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：7179 / 7182

页数：4

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