Carbon-carbon cross-coupling reactions under continuous flow conditions using poly(vinylpyridine) doped with palladium

被引：47

作者：

Mennecke, Klaas ^{[1
]}

Solodenko, Wladimir ^{[1
]}

Kirschning, Andreas ^{[1
]}

机构：

[1] Leibniz Univ Hannover, Inst Organ Chem, D-30167 Hannover, Germany

来源：

SYNTHESIS-STUTTGART | 2008年 / 10卷 / 10期

关键词：

palladium catalyst; immobilization; microreactor; microwave; C-C cross-coupling reactions;

D O I：

10.1055/s-2008-1072579

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Coordinative immobilization of an oxime-based pallada-cycle to poly(vinylpyridine)/glass composite materials shaped as Raschig rings or placed within the PASSflow(TM) microreactor affords technical devices that are well suited for performing palladium-catalyzed carbon-carbon cross-coupling reactions in the flow-through mode. Reusability of the immobilized precatalyst as well as applications in the microwave field were investigated. Experiments with thiol- and pyridine-based scavengers were carried out, which revealed that the active palladium species is likely to be composed of nanoparticles of unknown nature and that the poly(vinylpyridine) carrier has scavenging properties for these particles.

引用

页码：1589 / 1599

页数：11

共 25 条

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