An enantioselective synthesis of heteroaromatic N-tosyl α-amino acids

被引：153

作者：

Johannsen, M ^{[1
]}

机构：

[1] Tech Univ Denmark, Dept Organ Chem, DK-2800 Lyngby, Denmark

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 21期

关键词：

D O I：

10.1039/a906758b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new synthesis of optically active beta-indolyl and pyrrolyl N-tosyl alpha-amino acids has been developed which uses readily available starting materials and proceeds with a high degree of enantioselection, giving the alpha-amino acids with up to 96% enantiomeric purity in 89% yield using 1-5 mol% of a chiral copper(I)-Tol-BINAP catalyst.

引用

页码：2233 / 2234

页数：2

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