THE ROLE OF INTESTINAL TIGHT JUNCTIONS IN PATHOGENESIS OF NECROTIZING ENTEROCOLITIS

被引：0
作者：
Borys, Franciszek [1 ]
Sibrecht, Greta [1 ]
Naskrecka, Dobrochna [1 ]
Wroblewska-Seniuk, Katarzyna [1 ]
Mazela, Jan [1 ]
机构：
[1] Dept Newborns Infect Dis, Poznan, Poland
来源：
POSTEPY BIOLOGII KOMORKI | 2018年 / 45卷 / 04期
关键词：
tight junctions; necrotizing enterocolitis; breast milk; probiotics; preterms; HUMAN-MILK; BARRIER DYSFUNCTION; RANDOMIZED-TRIAL; PRETERM FORMULA; GROWTH-FACTOR; BREAST-MILK; INFANTS; ERYTHROPOIETIN; GLUTAMINE; LACTOFERRIN;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Tight junctions are multiprotein junctional complexes fastening intestinal epithelial cells together. Their function is to regulate paracellular permeability and to maintain integrity of intestinal epithelial barrier. Disruption of this barrier is believed to be involved in necrotizing enterocolitis development in preterm infants. In this review article we would like to present recent studies involving the role of tight junctions in the pathogenesis of necrotizing enterocolitis and also analyse impact of breastmilk components and probiotics on this process.
引用
收藏
页码：269 / 282
页数：14
相关论文
共 50 条
  • [21] Potential role of bile acids in the pathogenesis of necrotizing enterocolitis
    Yang, Jiahui
    Chen, Xiaoyu
    Liu, Tianjing
    Shi, Yongyan
    LIFE SCIENCES, 2024, 336
  • [22] Enteral feeding composition and necrotizing enterocolitis
    de la Cruz, Diomel
    Bazacliu, Catalina
    SEMINARS IN FETAL & NEONATAL MEDICINE, 2018, 23 (06) : 406 - 410
  • [23] Role of lactadherin in intestinal barrier integrity in experimental neonatal necrotizing enterocolitis
    Shen, Haiqing
    Lei, Yihui
    He, Xuemei
    Liu, Danyang
    He, Zhenjuan
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 120 (12) : 19509 - 19517
  • [24] The Protective Role of Intestinal Alkaline Phosphatase in Necrotizing Enterocolitis
    Whitehouse, Jill S.
    Riggle, Kevin M.
    Purpi, David P.
    Mayer, Alan N.
    Pritchard, Kirkwood A., Jr.
    Oldham, Keith T.
    Gourlay, David M.
    JOURNAL OF SURGICAL RESEARCH, 2010, 163 (01) : 79 - 85
  • [25] The role of intestinal alkaline phosphatase in the development of necrotizing enterocolitis
    Martins, Raquel Dos Santos
    Kooi, Elisabeth M. W.
    Poelstra, Klaas
    Hulscher, Jan B. F.
    EARLY HUMAN DEVELOPMENT, 2023, 183
  • [26] Role of Intestinal Microflora on Necrotizing Enterocolitis in Preterm Infants
    Wu, Lijuan
    Lin, Hung-Chih
    JOURNAL OF PEDIATRIC BIOCHEMISTRY, 2015, 5 (02) : 55 - 59
  • [27] Editorial: Intestinal Microbiota in the Pathogenesis and Management of Necrotizing Enterocolitis in Preterm Infants
    Guo, Chunbao
    Shi, Yuan
    FRONTIERS IN PEDIATRICS, 2022, 10
  • [28] Clinical Presentation and Multifactorial Pathogenesis of Necrotizing Enterocolitis in the Preterm Infant
    Andrews, Rachael E.
    Coe, Kristi L.
    ADVANCES IN NEONATAL CARE, 2021, 21 (05) : 349 - 355
  • [29] Intestinal epithelial tight junctions and permeability can be rescued through the regulation of endoplasmic reticulum stress by amniotic fluid stem cells during necrotizing enterocolitis
    Li, Bo
    Lee, Carol
    Chuslip, Sinobol
    Lee, Dorothy
    Biouss, George
    Wu, Richard
    Koike, Yuhki
    Miyake, Hiromu
    Ip, Wan
    Gonska, Tanja
    Pierro, Agostino
    FASEB JOURNAL, 2021, 35 (01)
  • [30] Genes regulating tight junctions and cell adhesion are altered in early experimental necrotizing enterocolitis
    Hogberg, Niclas
    Stenback, Anders
    Carlsson, Per-Ola
    Wanders, Alkwin
    Lilja, Helene Engstrand
    JOURNAL OF PEDIATRIC SURGERY, 2013, 48 (11) : 2308 - 2312
12345