A New Cytotoxic Polyacetylenic Alcohol from a Sponge Callyspongia sp.

被引：0

作者：

Balansa, Walter ^{[1
,2
]}

Trianto, Agus ^{[3
]}

de Voogd, Nicole J. ^{[4
]}

Tanaka, Junichi ^{[1
]}

机构：

[1] Univ Ryukyus, Dept Chem Biol & Marine Sci, Nishihara, Okinawa 9030213, Japan

[2] Nusa Utara Polytech, Dept Fisheries & Marine Sci, Tahuna Sangihe Isl 95812, North Sulawesi, Indonesia

[3] Diponegoro Univ, Dept Marine Sci, Tembalang Semarang 50275, Central Java, Indonesia

[4] Naturalis Biodivers Ctr, POB 9517, NL-2300 RA Leiden, Netherlands

来源：

NATURAL PRODUCT COMMUNICATIONS | 2017年 / 12卷 / 12期

关键词：

Callyspongia; Sponge; Polyacetylene; Cytotoxicity; MARINE SPONGE; METABOLITES; LEMBEHYNE;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new cytotoxic polyacetylenic alcohol 1 was isolated from an Indonesian sponge Callyspongia sp. The structure of compound 1 was elucidated by spectral analyses and by applying modified Mosher's method. Compound 1 killed the cultured NBT-II rat bladder carcinoma cells at 5 and 10 mu g/mL.

引用

页码：1909 / 1911

页数：3

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